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Overview of Clinical Characteristics

CF is characterized by viscous secretions affecting the lungs, pancreas, sweat glands, small intestines, liver, and reproductive system. The majority of CF patients demonstrate chronic obstructive pulmonary disease, pancreatic insufficiency, and elevated sweat electrolytes. CF is also associated with male infertility. (See Figure 1 below).

Figure 1

Image is courtesy of US Department of Health and Human Services. National Heart, Lung, and Blood Institute website. Available at: Accessed December 7, 2014.