Laboratory Diagnosis of Cystic Fibrosis (Online CE Course)

(based on 449 customer ratings)

Author: Vicky LeGrys, DA, MT(ASCP)
Reviewer: Rebecca J. Laudicina, PhD, MLS(ASCP)CM

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This course discusses the clinical presentation of cystic fibrosis (CF) and how genetic mutations can lead to the manifestation of the disorder. Laboratory testing used in the diagnosis of CF is presented including the components of a quantitative sweat chloride test. Finally, current treatment options for the disease are discussed.

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Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 1 hour(s)
Approved through 6/30/2023
Florida Board of Clinical Laboratory Personnel Credit Hours - General (Clinical Chemistry/UA/Toxicology): 1 hour(s)
Approved through 9/1/2022

Objectives

  • Describe the clinical presentation of cystic fibrosis (CF).
  • Describe how mutations in the CF gene lead to the clinical manifestations of the disorder.
  • Outline the laboratory diagnosis of CF to include newborn screening, the sweat test, and DNA testing.
  • Describe the components of a quantitative sweat chloride test to include reference ranges.
  • Compare screening sweat tests to confirmatory sweat tests.
  • Discuss the current treatment options for CF.

Customer Ratings

(based on 449 customer ratings)

Course Outline

Click on the links below to preview selected pages from this course.
  • Introduction to Cystic Fibrosis
  • The History of CF
      • History of CF and Diagnostic Testing
  • Pathophysiology of CF
  • Clinical Presentation
      • Overview of Clinical Characteristics
      • Pulmonary Disease
      • Pancreatic Disease
      • Sweat Gland Involvement
      • Gastrointestinal and Liver Disease
      • Reproductive System
      • Which of the following pathogens is associated with CF pulmonary disease?
      • Which of the following statements concerning the sweat of patients with CF is TRUE?
  • Laboratory Diagnosis of CF
    • Sweat Testing
      • Sweat Testing
      • Sweat Stimulation
      • Sweat Collection
      • Collecting An Adequate Sweat Sample
      • Quantitative Sweat Analysis
      • Screening Tests for Sweat
      • Reference Intervals for Sweat Chloride
      • Reference Intervals for Sweat Conductivity
      • Quality Assurance for Sweat Testing
      • CF is the only disorder that will result in increased sweat chloride concentrations.
      • When performing sweat testing for CF diagnosis, how long is sweat stimulated by iontophoresis and how long is it collected?
  • Treatment
  • Summary
      • Summary
  • References
      • References

Additional Information

Level of instruction: Intermediate

Intended Audience: Medical laboratory scientists, medical technologists, and technicians. This course is also appropriate for medical laboratory science students and pathology residents.

Author information: Vicky LeGrys, DA, MT(ASCP) is a professor in the Division of Clinical Laboratory Science in the School of Medicine at the University of North Carolina Chapel Hill where she is responsible for the lecture and laboratory courses in Biochemistry, Clinical Chemistry, and Quality Assurance. She holds a Doctorate of Arts and a Master of Science in Medical Technology from Catholic University of America, Washington DC with a major in Clinical Chemistry.
 
Reviewer information: Rebecca J. Laudicina, PhD, MLS(ASCP)CM is Professor Emeritus in the Division of Clinical Laboratory Science at The University of North Carolina at Chapel Hill’s School of Medicine. She obtained a Master of Education and PhD in Educational Psychology from Temple University. She is the author of numerous hematology-related publications.

How to Subscribe
MLS & MLT Comprehensive CE Package
Includes 141 CE courses, most popular
$95Add to cart
Pick Your Courses
Up to 8 CE hours
$50Add to cart
Individual course$20Add to cart
Need multiple seats for your university or lab? Get a quote
Sweat gland Normal CF


clinical characteristics


CFTR mutant


collection of sweat into macroduct_edit


digital chloridometer_edit