As previously mentioned, other tests exist to differentiate between myeloid and lymphoid lines. One way is to use monoclonal antibodies to detect surface markers on the cells. This is done using flow cytometry techniques, which will be described in more detail later. Regarding initial differentiation, however, Table 4 is helpful in differentiating the major cell lines.
Table 4. Differentiation between Myeloid and Lymphoblastic Leukemias Using CD Markers.| Cell Lineage | CD Markers |
| Myeloid | CD13, CD33, CD15, CD117 |
| T-Cell | CD2, CD3, CD4, CD5, CD7, CD8 |
| B-Cell | CD19, CD20, CD22, CD79a |
| Megakaryoblastic | CD41, CD61 |
