Course Outline
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- Definition and Differentiation of Acute Leukemia from Other Neoplastic Disorders
- Causes and Risk Factors of Acute Leukemia
- Introduction to the Classification and Diagnosis of Acute Leukemia
- Acute Myeloid Leukemia Diagnosis
- Signs and Symptoms of Acute Myeloid Leukemia
- 2022 WHO Classification of AML
- AML Laboratory Testing
- Basics of Laboratory Testing
- Cytogenetic Analysis
- Molecular Genetics of AML
- Karyotyping used in the diagnosis of AML refers to:
- AML is commonly caused by mutations that regulate:
- True or False: When studying the genome of an acute leukemia patient, mutations can be found that are unrelated to the leukemia.
- AML Prognosis and Treatment
- Prognostic Factors of AML
- Types of AML Treatments
- Newer Treatments
- Method of AML Treatment
- Prognosis of AML
- Important factors that can help determine a patient's prognosis of AML include all of the following except:
- What is the mechanism of action of chemotherapeutic drugs known as alkylating agents?
- Acute Lymphoblastic Leukemia Diagnosis
- Signs, Symptoms, and Background of Acute Lymphoblastic Leukemia
- Diagnosing ALL
- True or False: Adults very rarely get ALL; it is typically only found in children.
- 2022 WHO Classification of ALL
- WHO ALL Classification
- All of the following are classification criteria in the WHO classification system of ALL except:
- True or False: An essential point of differentiation in the WHO classification system of ALL is whether the disorder is leukemia or lymphoma.
- ALL Laboratory Testing
- Determination of ALL Lineage
- Chromosomal Analysis
- Genetic Analysis
- A three-year-old has been diagnosed with ALL. Chromosomal analysis performed on this child's lymphocytes showed 53 chromosomes. Which of the following...
- ALL Prognosis and Treatment
- Prognostic Factors for ALL
- Common Cytogenetic Abnormalities and their Prognosis
- Treatment of ALL
- The Future of ALL Therapy
- A two-year-old is diagnosed with ALL. Choose the characteristic that would yield the most favorable prognosis for this child.
- Acute Leukemia of Ambiguous Lineage and Mixed-Phenotype Acute Leukemia
- Acute Leukemia of Ambiguous Lineage
- Blastic Plasmacytoid Dendritic Cell Neoplasm
- True or False: Acute leukemia of ambiguous lineage (ALAL) is a common leukemia in which the lineage cannot be specified or shows features of both lymp...
- References
Additional Information
Level of Instruction: Intermediate
Intended Audience: Medical laboratory scientists, medical laboratory
technicians, laboratory supervisors, and laboratory managers. This course is
also appropriate for MLS and MLT students and pathology residents.
Author Information: Margaret Reinhart, MS, MLS(ASCP) serves as Senior Lecturer Emerita in Biological Sciences at Saint Joseph's University (formerly University of the Sciences) in Philadelphia, PA, and served as Program Director of Medical Laboratory Science from 1990 to 2020. She also taught hematology, clinical immunology, parasitology, and other related courses. She is currently an adjunct medical laboratory science instructor at Pennsylvania Hospital in Philadelphia, PA. She holds a master's degree in biology and in health care administration.
The author has no conflict of interest to disclose.
Reviewer Information: Joshua J. Cannon, MS, MLS(ASCP)CMSHCM received his Bachelor
of Science and Master of Science in Medical Laboratory Science from Thomas
Jefferson University in Philadelphia, PA. He holds Medical Laboratory Scientist
and Specialist in Hematology certifications through the ASCP Board of
Certification. He was a professor at Thomas Jefferson University for seven
years before transitioning into his current role as Education Developer at
MediaLab. His areas of expertise and professional passions include clinical
hematology and interprofessional education.
