Disseminated Intravascular Coagulation (DIC)

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Disseminated Intravascular Coagulation (DIC)

DIC is a condition that is usually secondary to an underlying disease or condition. Some DIC activators are sepsis, placenta abruption, snake bites, toxin, trauma, graft vs. host disease, and burns.
The mechanisms involved in DIC include a hyperactivated coagulation system, a hyperactivated fibrinolytic system, or both simultaneously. In most cases, the coagulation factors are consumed as soon as they are made and platelets are also consumed in the coagulation process. Clots are made rapidly and then destroyed as the fibrinolytic system is hyperactivated, leading to an increased risk of bleeding complications.