Chronic Idiopathic Thrombocytopenic Purpura

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The page below is a sample from the LabCE course Authentic and Spurious Causes of Thrombocytopenia. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Chronic Idiopathic Thrombocytopenic Purpura

Chronic ITP occurs most often in females 20 - 40 years of age. Platelet counts usually range between 30 - 50 x 109/L, and patients may or may not be symptomatic. Symptoms, when they occur, may include epistaxis and ecchymoses.
Autoantibodies directed toward epitopes on GP IIb/IIIa or GP Ib/IX are detected in about 50 - 80% of patients with chronic ITP.

A patient with epistaxis (nosebleed).