Graft Versus Tumor Effect

How to Subscribe
MLS & MLT Comprehensive CE Package
Includes 175 CE courses, most popular
$109Add to cart
Pick Your Courses
Up to 8 CE hours
$55Add to cart
Individual course$25Add to cart
Need multiple seats for your university or lab? Get a quote
The page below is a sample from the LabCE course Hematopoietic Stem Cell Transplantation. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

Learn more about Hematopoietic Stem Cell Transplantation (online CE course)
Graft Versus Tumor Effect

Early studies of allogeneic stem cell transplants found an interesting effect in which transplanted immune cells had a powerful response to tumor cells. This response was the result of differences in minor mHA antigens between the donor and recipient. As a result, now leukemia patients can limit the toxic chemotherapy used to control their disease. Another therapy, use of donor lymphocytes for prevention of relapse, has been shown to be as effective as an anti-tumor agent. This is especially helpful if the original transplant was conditioned to remove donor T-cells.