New Oral Anticoagulants (Online CE Course)

(based on 522 customer ratings)

Author: Mary L. Turgeon, Ed.D., MLS(ASCP)CM Reviewers: Rory Huschka, M.Ed., MLS(ASCP) and Laurie Bjerklie, M.Ed., MLS(ASCP)

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This course addresses some of the new oral anticoagulants that are being used and some of the challenges faced when using traditional coagulation tests to assess the drug effects. Strategies for effectively monitoring these new therapeutic drugs, along with the advantages and disadvantages of their use, are discussed.

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Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 1 hour(s)
Approved through 11/30/2024
Approved through 11/30/2024

Objectives

  • Review the principles of the normal blood coagulation clotting cascade.
  • Compare the characteristics and associated mode of actions of the four FDA-approved new oral anticoagulants (NOACs).
  • Name the FDA approved clinical applications of various anticoagulant therapies.
  • Describe the NOACs specimen processing, storage and shipping requirements.
  • Compare first-line common and NOAC specific laboratory coagulation assessment procedures.
  • Summarize the clinical interpretations of coagulation testing results including potential interference factors.
  • Describe the two approved bleeding reversal agents mode of action.

Customer Ratings

(based on 522 customer ratings)

Course Outline

Click on the links below to preview selected pages from this course.
  • Coagulation Overview
      • Coagulation Cascade Overview
      • Pathways for Coagulation
    • Pathways
      • Extrinsic Pathway
      • Intrinsic Pathway
      • Common Pathway
      • Fibrin Clot and Fibrinolysis
      • The intrinsic pathway for coagulation begins with the activation of which of the following factors?
      • The final common pathway begins with the activation of which of the following factors?
      • Case Study #1
  • Traditional and New Oral Blood Anticoagulants
      • Traditional and New Oral Anticoagulants (NOACs)
    • Traditional Blood Anticoagulants
      • Traditional Anticoagulants
      • Heparin inhibits the clotting of blood by neutralizing the effect of which of the following?
      • Warfarin is an antagonist of which of the following vitamins?
    • New Oral Anticoagulants (NOACs)
      • New Oral Anticoagulants (NOACs)
      • Thrombin Inhibitor
      • Factor Xa Inhibitors
      • Which of the NOACs impacts thrombin?
  • Clinical Applications of Novel Oral Anticoagulants
  • Laboratory Assessment
  • Impact of NOACs on Other Coagulation Assays of Importance
      • Impact of NOACs on Other Coagulation Assays
      • NOAC Impact on Antithrombin Activity and Activated Protein C Resistance
      • NOAC Impact on Coagulation Factors and Fibrinogen
      • NOAC Impact on Lupus Anticoagulants and Protein C/Protein S Activity
  • Specimen Collection and Processing
      • Specimen Collection and Processing
      • A blood specimen from a patient receiving anti-Xa therapy can be stored for a maximum of how many hours after collection?
      • After collection, a plasma specimen from a patient receiving NOAC therapy can be stored in a freezer for a maximum of how long?
  • Interpretation of Test Results
  • Anticoagulation Reversal Agents
      • Anticoagulation Reversal Agents
      • Which of the following reversal anticoagulant therapies is appropriate for patients being treated with dabigatran who experience massive bleeding?
  • Conclusion
      • Conclusion
  • References

Additional Information

Level of Instruction:  Intermediate
Intended Audience:  Practicing medical laboratory scientists (MLS), medical laboratory technicians (MLT), MLS students, and MLT students.
Author Information:  
Mary Louise Turgeon, Ed.D, MLS(ASCP)CM, is the author of four medical laboratory science textbooks: Basic & Applied Clinical Laboratory Science (8 ed), Elsevier(2020); Immunology and Serology in Laboratory Medicine (7 ed), Elsevier (2022); Clinical Hematology (6 ed), Lippincott-Williams & Wilkins (2018); and Fundamentals of Immunohematology 2 ed). Foreign language editions have been published in Chinese, Spanish, and Italian.
Dr. Turgeon has 18 years of university and 15 years of community college teaching and program administration experience. Guest speaking, scientific presentations, and technical and educational workshops complement her teaching and writing activities. 
Reviewer Information: 
Rory Huschka, M.Ed., MLS(ASCP) is a Content Developer at MediaLab Inc. He holds a BS degree from North Dakota State University in Medical Technology and an MS degree in Educational Leadership. He is a former Program Director for both MLT and MLS programs. Rory continues to teach as an adjunct professor for various colleges and universities.
Laurie Bjerklie, M.Ed., MLS(ASCP) is a Content Developer at MediaLab Inc.  She is a former Program Director for MLT and MLS programs and continues to work as an adjunct in various MLT and MLS programs.  
Course Description:  
This course addresses some of the new oral anticoagulants that are being used and some of the challenges faced when using traditional coagulation tests to assess the drug effects.   Strategies for effectively monitoring these new therapeutic drugs along with advantages and disadvantages of their use are discussed.  

How to Subscribe
MLS & MLT Comprehensive CE Package
Includes 178 CE courses, most popular
$109Add to cart
Pick Your Courses
Up to 8 CE hours
$55Add to cart
Individual course$25Add to cart
Need multiple seats for your university or lab? Get a quote
Thrombus in the pulmonary artery


Common pathway


Factor X