Course Outline
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- Defining Thalassemia
- Defining Thalassemias
- Defining Beta Thalassemia
- Beta Thalassemia Genetics Overview
- Anemia in Beta Thalassemia
- Which chromosome demonstrates a partial or full gene loci deletion in various forms of beta thalassemia?
- Clinical Manifestations of Beta Thalassemia
- Genetics of Beta Thalassemia
- Laboratory Findings in Beta Thalassemia
- Hematologic Findings For Various Types of Beta Thalassemia
- Serum Iron
- Serum Bilirubin
- Codocytes (target cells) are a typical finding in which of the following types of beta thalassemia?
- Special Procedures
- Hemoglobin Electrophoresis
- Hemoglobin Electrophoresis Theory
- Migration of Hemoglobin in Alkaline Electrophoresis
- Normal Hemoglobin Electrophoresis
- Normal Hemoglobin Electrophoresis Densitometer Tracing
- Hemoglobin Electrophoresis Patterns in Beta Thalassemia
- Case Study
- Case History
- Laboratory test results
- Laboratory Test Results
- The CBC results in this case break the rule of three. What is the rule of three?
- Why is it important to note that the red cell distribution width (RDW) in this case is normal ?
- This is a representative field from the patient's peripheral blood smear.What RBC morphology is prominent on this patient's smear?
- Hemoglobin Electrophoresis
- Hemoglobin electrophoresis on this patient's sample is pictured above and is labeled "patient 2" in lanes 5 and 6. The densitometer tracing of lane 5 ...
- Summary of Case Study
- What is this patient's most likely diagnosis?
Review of results:
This patient has an increased RBC count with a decreased Hb and normal Hct. The M...
- Case History Summary
- References
Additional Information
Level of instruction: Intermediate
Intended Audience: Medical laboratory technologists and technicians and other health care personnel who have an interest in this subject matter. This course is also appropriate for clinical laboratory science students and pathology residents.
Author Information: Lillian Mundt, EdD, MLS(ASCP)SH is currently employed by AMITA Adventist Hinsdale Hospital in the Molecular Pathology Department. She received her Bachelor of Arts degree in Medical Technology from Aurora College, Aurora, Illinois. Her graduate work was completed at Governor's State University, University Park, Illinois, from which she received her Master of Health Science in Allied Health Professions Education; her doctorate in Educational Leadership was earned from the University of Phoenix. Her work experience includes a position as a medical technologist in hematology for 30 plus years at Hinsdale Hospital, Department of Pathology. Lillian also taught at Hinsdale Hospital School of Medical Technology from 1981 until it closed in 1994 and Rosalind Franklin University of Medicine and Science Department of Clinical Laboratory Sciences from 1994 until the program closed in 2009.
Reviewer Information: Catherine Hart, MT(ASCP) received her Bachelor of Science degree in Medical Technology at Marquette University. She has been a Medical Technologist at Lake Forest Hospital in Illinois for twenty years and is currently a Senior Technologist, with responsibilities in Blood Bank, Hematology, and the competency and proficiency testing program of the laboratory. Ms. Hart has been the adjunct Blood Bank instructor for the Clinical Laboratory Sciences program at Rosalind Franklin University since 2001 and is the Blood Bank clinical instructor at Lake Forest Hospital. As of May 2007, she joined the RFUMS CLS appointed faculty and is teaching the Hematology and Blood Bank courses.
Course Description: This course defines and discusses in depth the disorder, beta thalassemia. Topics include: Clinical manifestations, the genetics of beta thalassemia, and laboratory findings.
