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The page below is a sample from the LabCE course Beta Thalassemia. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Chromosome 11 Delta-Beta Thalassemia Intermedia

Delta-beta thalassemia intermedia exists when both gene loci for beta and delta chains are deleted or inactive on one chromosome, while the other chromosome contains a beta chain gene that is partially deleted or inactive. Delta-Beta 0/ Beta+

In this state the majority of hemoglobin will be Hb F, with very little Hb A and A2 present.

(drawing modified from Harmening, 1999)