Tracking Antibiotic-Resistant Tuberculosis (Online CE Course)

(based on 327 customer ratings)

Author: Cynthia B. Schofield, MPH, MT
Reviewer: Catherine Dragoni, MT(ASCP)SM

In this course, the presentation of a brief history of tuberculosis (TB) and its developing resistance to anti-tuberculosis drugs, is followed by case histories from India, Italy, and the US-Mexican border. The pathogenesis of TB disease in humans is diagrammed and a review of diagnostic laboratory methods, susceptibility testing, and methods of control are explored.

See all available courses »

Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 2 hour(s)
Course number 578-062-16, approved through 7/31/2018
Florida Board of Clinical Laboratory Personnel Credit Hours - General (Microbiology/Mycology/Parasitology): 2 hour(s)
Course number 20-547961, approved through 9/1/2018


  • Review the history of Mycobacterium tuberculosis (MTB) and developing antibiotic resistance.
  • Discuss the global case load of tuberculosis (TB), including India, Italy, and the United States (US)-Mexican border.
  • Describe two pediatric TB cases.
  • Diagram and explain MTB pathogenesis.
  • Discuss laboratory methods of MTB diagnosis and susceptibility testing.
  • Review methods of TB treatment and control.

Customer Ratings

(based on 327 customer ratings)

Course Outline

Click on the links below to preview selected pages from this course.
  • Introduction
      • Epidemiology of Multidrug-Resistant Tuberculosis (MDR-TB)
  • Background
      • History
      • Robert Koch made several significant discoveries with regard to the tuberculosis (TB) bacillus. Which statement is FALSE?
      • Early Treatment
      • TB Wonder Drugs
      • Transmission
      • For tuberculosis (TB) patients, the success of sanatorium treatment was based on a combination of several different factors. Which of the factors list...
      • Spread of Resistance: Escalation of Multidrug-Resistant Tuberculosis (MDR-TB)
      • In the 1980s, what major factor directly caused the escalation of multidrug-resistant tuberculosis (MDR-TB)?
      • Spread of Resistance: Global Emergency
      • After the first appearance of extensively drug-resistant tuberculosis (XDR-TB), which control measure was the MOST effective?
  • Global View
      • India
      • Development of Selective Resistance in India
      • Which of the following statements BEST explain India’s rising prevalence of totally drug-resistant tuberculosis (TDR-TB)? (Choose all that apply...
      • Italy
      • Source of Infection in Italian School Epidemic
      • Which three (3) statements help to explain the difficulty in resolving the multidrug-resistant tuberculosis (MDR-TB) epidemic in the Italian school? (...
      • Case Study of Drug Resistance in Two Children: Patient 1
      • Case Study of Drug Resistance in Two Children: Patient 2
      • Case Study of Drug Resistance in Two Children: Treatment Summary for Both Cases
      • Comparison of Italian Pediatric Cases
      • Which of the following statements accurately describe the similarities present in both of the pediatric case studies presented? (Choose all that apply...
      • United States (US)-Mexican Border
      • United States (US)-Mexican Border, continued
      • What primary factors tend to increase the incidence of multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant TB (XDR-TB) across the...
  • Pathogenesis
  • Laboratory Diagnosis
  • Treatment and Control of Antibiotic-resistant TB
      • Treatment
      • Control and Prevention
      • Which of the following statements are considered essential to the treatment and control of MDR-TB? (Choose all that apply.)
  • Looking Ahead
  • References
      • References

Additional Information

Level of instruction: Basic to intermediate 

Intended audience:  This course is intended for microbiology bench technicians and technologists, supervisors, and administrators. 

Author information: Cynthia B. Schofield, MPH, MT received her BS degree in Biology at the University of Michigan, Ann Arbor, Michigan and her Masters of Public Health, Epidemiology, and Biostatistics at San Diego State University, San Diego, California. Cynthia is retired with 25 years of supervisory experience in the clinical microbiology laboratory and has written for numerous publications, including ASCP, Advance, and MLO.

Reviewer information: Catherine Dragoni, MT(ASCP)SM received her BS degree in Medical Technology from the State University of New York, Upstate Medical Center, Syracuse. She began her career as a bench microbiologist at Maine Medical Center, Portland, Maine. Currently she is the Chief Technologist of Microbiology and Molecular Pathology at NorDx Laboratories, Scarborough, Maine.

Course description: In this course, the presentation of a brief history of tuberculosis (TB) and its developing resistance to anti-tuberculosis drugs, is followed by case histories from India, Italy, and the US-Mexican border. The pathogenesis of TB disease in humans is diagrammed and a review of diagnostic laboratory methods, susceptibility testing, and methods of control are explored.


These are the most common topics and keywords covered in Tracking Antibiotic-Resistant Tuberculosis:

beacons puentes multidrug-resistant antibiotics 11-month-old apical non-sterile concentrate appears nucleic aspirates non-infectious numbers second-line organism dosages assay clinics mtbc pigs identification combinations specimens hinduja drug staffing badly hospital capreomycin lungs mycolic vertebral hydroxide mgit endemic co-infection anti-tb antibiotic meningitis italy antimicrobial middlebrook respiratory vaccine organisms agar esp#174 sodium glycerol out-of-control colony immune ethionamide mantoux pyrazinamide sanatorium chromatography funding officially diagnostic rifabutin microbiology primed linezolid reinfection calmette-guerin cavitation clinical sterile sanatoria brains mycobacteria liquefy indian first-line health guidelines diagnostics rflp proved vessels fathers infection south germany china reactivation underestimate untreatable phagocytized helped diagnosis kanamycin potato symptoms p-aminosalicylic fluorescence-quenching rpob workers methods bactec safety amplification becton-dickinson mucolytic pathogenesis inoculation epidemiological polymorphism eradicating suffer tubercle fluorescence dosage direct-observed scrofula sensitivity novel advancing naoh isoniazid aids sputum trek cells gastric liquefaction oxford laboratory bacille revolutionary polymerase nuclei amikacin udwadia tijuana journals perihilar alveolar bacteria lymphatic cipro enzymes airway extensively genotyping coughing xxdr-tb vaccinated hepa procedures bactec#8482 cepheid biosafety aunt granuloma mammals x-ray inoculated mexico salvage xdr- kindergarten moxifloxacin macrophage infection control lymph concentration mycobacterium ethambutol tdr-tb infectious n-acetyl-l-cysteine presumed specificity prohibitive xdr-tb spoligotyping gene paramount bacterial caseous baja disease declined bacterium simplicity epidemiology aerosols rntcp mycobacterial york july assays acid-fast -mexican italian sensor oadc outbreak monocytes smear-positive treatment pediatric culture-positive cycloserine mumbai diseases inoculum levofloxacin anti-tuberculosis streptomycin rifampin cure-rate hilar scientists dramatic blood bacillus koch lowenstein-jensen mdr-tb 23-month-old benefited inoculating radiometric oxygen mdr- statistics state-of-the-art superbug matched genexpert#174 first- escalation xpert#174 cellular tuberculin meta-analysis in-tube cattle iran toxic naats news drug-resistant totaled contamination geneva respirology horrendous inactivation lived semi-automated macrophages exams debilitating infiltrate lung morphology globally drug-containing droplet sneezing discovery interferon-gamma relaxed management naat methylene adverse exposure deter mgit#8482 contains allows devastating prescribed esperanza ancient indias hplc culture conditions ciprofloxacin kochs infiltrates igra hospitalization advocacy acids
How to Subscribe
MLS & MLT Comprehensive CE Package
Includes 94 CE courses, most popular
$95 Add to cart
Pick Your Courses
Up to 8 CE hours
$50 Add to cart
Individual course$20 Add to cart

2174 mtb acidfast fig7ASM Microbe Libe

AFB fluorescent stain, courtesy of the CDC.

Fluorescent auramine stain w/acridine orange counterstain

MTB by Ziehl-Neelsen


TB susceptibility agar proportion test, courtesy of CDC.

Ziehl-Neelson stained MTB showing AFB w/cording morphology, courtesy of the CDC