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The page below is a sample from the LabCE course White Cell and Platelet Disorders: Peripheral Blood Clues to Nonneoplastic Conditions. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Thrombocytosis Associated with Toxic Granulation

Thrombocytosis is the term used for an increase in platelets secondary to a synergistic or sympathetic response of increased bone marrow activity. This increase in platelets may accompany a variety of infectious or inflammatory conditions displaying neutrophilia and toxic granulation. Thrombocytosis accompanying toxic granulation can be seen in the image on the right.