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The page below is a sample from the LabCE course Chemical Screening of Urine by Reagent Strip. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Leukocytes Reaction, continued

Lymphocytes do not contain leukocyte esterase and would not produce a positive leukocytes test on the reagent strip.
Positive results should be confirmed by performing a microscopic examination of the sediment. Note that white blood cells would not be seen in the sediment if they have lysed; however, the leukocytes test on the reagent strip would still be positive because the test is based on the detection of esterase, which is still present in the urine.