Optimal Cardiac Biomarkers

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The page below is a sample from the LabCE course Cardiac Biomarkers. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Optimal Cardiac Biomarkers

An ideal marker for cardiac disease would have all of these characteristics:
  • It should be specific to myocardial tissue.
  • It should have low concentrations in normal (healthy) peripheral blood.
  • It should be rapidly released after myocardial injury.
  • It should be detected in low quantities, with little interference from other compounds.
  • The marker should remain in circulation for a sufficient length of time for detection.
  • The plasma concentration of the marker should be directly related to the extent of the injury.
  • The test for the biomarker should be easily automated, relatively inexpensive to run, and results should be obtained rapidly.