Summary

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The page below is a sample from the LabCE course Variations in White Cell Morphology -- Granulocytes. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Summary

Summary of Nuclear Variations
NameImages Description
Hypersegmentation
 More than 5 segments to the nucleus.
Associated with:
  • Megaloblastic Anemia
  • Myelodysplastic Syndromes
  • Chemotherapy
  • Long-term chronic infections
Hyposegmentation Two or fewer segments to the nucleus.
Associated with:
  • Infections
  • Burns
  • Malignancy
  • Chemotherapy and drugs
  • Pelger-Huet anomaly
Barr Bodies Small drumstick-like projection on one of the nuclear lobes.
Associated with:
  • Inactivated X chromosome