Döhle Bodies

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The page below is a sample from the LabCE course Variations in White Cell Morphology -- Granulocytes. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Döhle Bodies

Döhle bodies are small, light blue-gray, irregular-staining patches of cytoplasm seen near the edge of the cell in granulocytes in certain conditions. Electron microscopic examination reveals that they are composed of aggregates of rough endoplasmic reticulum remaining from an earlier stage of development.
The Döhle body in this cell can be seen near the edge of the cytoplasm, near the blue arrow tip.