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The page below is a sample from the LabCE course Red Blood Cell (RBC) Morphology. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

Learn more about Red Blood Cell (RBC) Morphology (online CE course)

The term stomatocyte is derived from the Greek term stoma, meaning mouth. Stomatocytes have elongated or slit-like central pallors, which may be curved, giving the central pallor an appearance of a smiling mouth. The occasional stomatocyte seen in normal smears is the result of a slight pH change in the environment, similar to the in vitro changes that cause cells to assume the echinocyte shape. Two stomatocytes are indicated by arrows on this slide.