Questions #9 and 10: Vaccinations and Close Contact with Smallpox Vaccine Recipient

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The page below is a sample from the LabCE course Donor Selection: The Donor History Questionnaire. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

Learn more about Donor Selection: The Donor History Questionnaire (online CE course)
Questions #9 and 10: Vaccinations and Close Contact with Smallpox Vaccine Recipient


YesNo
In the past 8 weeks, have you
9. Had any vaccinations or other shots?
10. Had contact with someone who was vaccinated for smallpox in the past 8 weeks?
Measles, mumps, polio, typhoid, yellow fever, or any other live attenuated or bacterial vaccine is a 14-day deferral following the vaccination. German measles (rubella) and chickenpox/shingles (varicella-zoster) vaccinations are a 4-week deferral after the vaccination. There is no deferral period for nonreplicating, inactivated, or mRNA-based COVID-19 vaccines or toxoid, synthetic, or killed viral, bacterial, or rickettsial vaccines as long as the donor is symptom-free and afebrile.
Deferral following a smallpox vaccine is 21 days or until the scab has fallen off, whichever is later. If the scab did not fall off on its own, the donor is deferred for 56 days from their vaccination date. Donors who have been in close contact with persons who have received the smallpox vaccination are also at risk, as the scab that forms as a result of vaccination contains infectious viral particles. The FDA does not recommend deferral for asymptomatic contacts of smallpox vaccine recipients, but donors displaying symptoms (new skin rashes or new skin sores) associated with the virus should be deferred from donation. Any donors who experienced complications as a result of either vaccination or exposure to someone who was vaccinated should also be deferred for at least 14 days following symptom resolution.
The JYNNEOS vaccine for mpox does not require any deferral.

A fully healed scar from the smallpox vaccine.