Screening for Fetomaternal Hemorrhage (FMH)

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The page below is a sample from the LabCE course Hemolytic Disease of the Fetus and Newborn. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

Learn more about Hemolytic Disease of the Fetus and Newborn (online CE course)
Screening for Fetomaternal Hemorrhage (FMH)

Several screening methods are available to detect FMHs that require additional RhIG, including:
  • Rosette method
  • Commercial fetal bleed screening tests
  • Gel agglutination fetal cell screening technique
Note: The rosette test may be falsely positive if the mother is weak-D positive and may be falsely negative if the baby is weak-D positive.
The rosette method, commonly used by many laboratories, will be briefly reviewed.