Bone Marrow Biopsy

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The page below is a sample from the LabCE course Bone Marrow Aspiration: Normal Hematopoiesis and Basic Interpretive Procedures. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Bone Marrow Biopsy

A bone marrow biopsy is obtained by a similar technique but rather than aspirating liquid marrow, a core of bone is allowed to enter the biopsy needle and is then removed within the needle. The image* illustrates the body site where the bone marrow is normally obtained.
The core can be rolled between two slides to make touch preparatons (touch preps), which are then stained and reviewed.
The bony core is fixed and sent to pathology, where it will be decalcified and prepared for sectioning and staining.
Reference: Bone marrow biopsy. National Cancer Institute. Available at: Accessed July 3, 2011.