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The page below is a sample from the LabCE course Biochemical Markers of Osteoporosis. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Medications (Anti- Seizure & Diuretics)

Anti-seizure and Mood-altering Drugs

The anti-seizure drugs carbamazepine (Tegretol) and phenytoin (Dilantin) have been associated with a reduction in bone density and this is believed to be due to low vitamin D and decreased intestinal absorption of calcium.
Furosemide (Lasix), is commonly used to treat the fluid retention and swelling caused by heart failure. It works by increasing urinary output and promotes calcium excretion from the kidneys. As a result, they have been associated with reduced bone mineral density at the hip.