The table below lists the reaction types that were previously described and summarizes additional testing that may be ordered.
Table 2: Additional TestingAcute Reaction Type
| Additional Testing
|
Anaphylactic
| - Anti-IgA
- IgA quantitative
|
Febrile nonhemolytic | - If initial testing is negative, perform a culture to rule out a bacterially-contaminated blood component.
- When other sources of the fever have been ruled out, the reaction is categorized as a febrile nonhemolytic transfusion reaction (FNHTR).
|
Hemolytic
| - Bilirubin
- Haptoglobin
- Lactate dehydrogenase (LDH)
|
Transfusion-associated bacterial sepsis
| - Gram stain
- Culture of component
- Blood culture of the recipient
|
Transfusion-associated circulatory overload (TACO)
| - Chest x-ray
- B-type natriuretic peptide (BNP)
|
Transfusion-related acute lung injury (TRALI)
| - Chest x-ray
- BNP
- Leukocyte antibody screens (donor and recipient plasma)
- Antigen typing of recipient
|