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The page below is a sample from the LabCE course Microbial Identification Using MALDI-TOF MS. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Instrument Selection

Currently, there are three instruments that perform microbial identification using MALDI-TOF MS:
  1. The Bruker Daltonik Microflex Biotyper (Billerica, MA)
  2. bioMérieux VITEK® MS (Durham, NC)
  3. Andromas SAS (Paris, France)
The first two instruments listed are available in the United States and have received clearance from the Food and Drug Administration (FDA) for identification of certain groups of microorganisms. The instruments are relatively simple in components and include a laser, a pump (to affect a vacuum in the flight tube), and a detector, all coordinated by electronic circuitry. These two systems differ in several ways, including size (foot print), sample throughput, time to result, consumables, target plates, preventative/routine maintenance, and automation capability. These differences are discussed on the next page.
The Andromas system is a database manufactured and maintained by Andromas SAS (Paris, France). Utilized predominantly for clinical diagnostics in Europe, the database is available in North America for research use only.