Inherited Antigens

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The page below is a sample from the LabCE course Introduction to the ABO Blood Group System. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

Learn more about Introduction to the ABO Blood Group System (online CE course)
Inherited Antigens

"A subgroup" antigens are inherited, as are other ABO antigens, with A1 being dominant over A2. Individuals who are phenotypically A1 may be genotypically A1O, A1A1, or A1A2. A phenotypically A2 individual may be genotypically A2A3. These alleles are passed to offspring in the same manner as other ABO antigens.
Weak variant forms of the B antigen (B3, Bx, and Bel) exist but are rare.