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The page below is a sample from the LabCE course Drug-Resistant Superbugs, Multi-drug Resistant Organisms: MRSA, VRE, Clostridium difficile, and CRE. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Interpretation of Oxacillin Broth Dilution Tests.

The CLSI document M100 is the definitive resource for all standard susceptibility interpretative criteria.
Oxacillin is the standard antibiotic incorporated into MIC testing algorithms to predict resistance to beta-lactam antibiotics. Breakpoints for oxacillin as defined by the CLSI are defined as follows:
Interpretative criteria for oxacillin and S. aureus:
Antibiotic
Susceptible
Intermediate
Resistant
Oxacillin
< 2µg/mL
--
> 4 µg/mL