The following chart describes fast-growing molds which are less often pathogenic.
Organism | Disease and Site | Identifying Features | Other Comments |
Alternaria spp. | Phaeohyphomycosis, sinus/nasal infection | Hyphae dematiaceous and septate. Golden brown hyphae have conidiophores with a chain of conidia resembling a drumstick. Produce dictyospores | Usually not pathogenic |
Aureobasidium pullulans | Skin, nails. Occasional phaehyphomycosis | Black yeast-like colonies. Conidia are hyaline and smooth-walled, single-celled ellipsoidal and variable shape and size (8-12 x 4-6 μm). Often has an indistinct hilum Note: Aureobasidium pullulans and Hortaea wernickii characteristically produce black yeasts throughout their maturation process. The young colonies of Exophiala jeanselmei may appear as a black yeast, being microscopically identical to Hortaea wernickii. | |
Bipolaris spp. | Phaeohyphomycosis, chronic sinusitis | Hyphae dematiaceous and septate. Conidiophores are bent where conidia attached. Multicelled macroconidia are oblong to fusoid and smooth walled and are pseudoseptate (diptosepta). Can produce polar germ tubes. Note: The macroconidia of Drechslera species are muriform - showing both longitudinal and transverse septation. They appear similar in many ways to Bipolaris, except that they appear longer and thinner. (Drechslera species also produce germ tubes upon incubation; however, they are single and emerge only from the hilar cell at a right angle.) | Usually not pathogenic |
Curvularia spp. | Phaeohyphomycosis, sinusitis | Hyphae dematiaceous and septate. Conidiophores are bent where conidia are attached. Macroconidia are brown, curved (boomerang- shaped) with a central enlarged cell; end cells are lighter and have distinct transverse septa | |
Epicoccum spp. | None; generally a clinical contaminant | When sporulating, numerous black sporodochia (aggregates of cushion-like conidiophores) are visible. Macroconidia are divided by longitudinal and transverse septa (dictyospores). | |
Exserohilum spp. | Phaeohyphomycosis | Hyphae dematiaceous and septate. Conidiophores are bent where conidia attached. Multi-celled macroconidia are long, pencil shaped and have a distinctive hilum (hilar cell extension)and have transverse septae. | |
Nigrospora spp. | Rarely pathogenic; usually a plant pathogen | Colony starts out white and wooly, but then darkens with maturity, turning black or brown. Single, globose, black conidia. | |
Scedosporium boydii (previously known as Pseudallescheria boydii) | Mycetoma, Phaeohyphomycosis | Has both sexual and asexual reproduction Conidia are golden brown and single-celled, and borne from tips of conidiophores Spores are in cleistothcia | See more info under the hyaline mold section. |
Scopulariopsis brumptii (other notable species include: S. brevicaulis, and S. gracilis.) | Rare cause of disease | Dematiaceous variation of the hyaline mold, Scopularopsis spp. Produces chains of large, lemon-shaped conidia with darkly staining bases, called annelloconidia: (S.brumptii) | |
Stemphylium spp. | Rare cause of disease | Dark brown, oblong, multicelled muriform conidia supported by a straight conidiophore “bale of cotton on a stick” (images courtesy of U. of Adelaide) | |
Ulocladium spp. | Keratitis | Numerous, usually solitary, multicelled divided conidia (dictyoconidia or dictyospores) are formed through a pore (poroconidia) by a sympodially elongating geniculate (bent) conidiophore(which differentiates it from Stemphylium) (second image courtesy of U. of Adelaide) | |