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The page below is a sample from the LabCE course HIV: Structure, Replication, and Detection. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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The Centers for Disease Control and Prevention (CDC) Recommended Algorithm for HIV Testing

In 2014, the CDC published a new HIV testing algorithm. The algorithm is shown below and can be found on the CDC website at: http://www.cdc.gov/hiv/pdf/hivtestingalgorithmrecommendation-final.pdf. Accessed June 27, 2016.
Note that if a fifth generation assay is used, differentiation of all three HIV analyte markers (antigen, HIV-1, and HIV-2 antibodies) occurs in the first step.