Myeloproliferative Neoplasms (Online CE Course)

(based on 379 customer ratings)

Author: Leah Coppolino, MPH, CLS(NCA), MT(ASCP)
Reviewer: Rebecca J. Laudicina, PhD, MLS(ASCP)CM

See all available courses »

Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 1 hour(s)
Course number 578-002-15, approved through 1/5/2017
Course number 20-547797, approved through 9/1/2018


  • Describe the 2008 World Health Organization classification system for myeloproliferative neoplasms (MPNs).
  • Compare and contrast the types of MPNs based upon etiology and patient symptoms.
  • Discuss the hematologic, cytogenetic, and other laboratory features associated with specific MPNs.
  • List common treatment options.

Customer Ratings

(based on 379 customer ratings)

Course Outline

Click on the links below to preview selected pages from this course.
  • Myeloproliferative Neoplasms
    • Chronic Myelogenous Leukemia
    • Chronic Neutrophilic Leukemia
      • Chronic Neutrophilic Leukemia (CNL)
      • Chronic Neutrophilic Leukemia (CNL), continued
    • Hypereosinophilic Syndrome/Chronic Eosinophilic Leukemia
      • Hypereosinophilic Syndrome (HES)
      • Chronic Eosinophilic Leukemia (CEL)
      • What causes the characteristic heart and/or lung damage frequently demonstrated in patients with chronic eosinophilic leukemia?
    • Essential Thrombocythemia
    • Primary Myelofibrosis
      • Primary Myelofibrosis (PMF)
      • Diagnosis of Primary Myelofibrosis (PMF)
      • Diagnosis of Primary Myelofibrosis: World Health Organization (WHO) Criteria
      • Which of the following red blood cell morphologic features is associated with primary myelofibrosis?
    • Polycythemia Vera
      • Polycythemia Vera (PV)
      • Diagnosis of Polycythemia Vera (PV)
      • Treatment of Polycythemia Vera
      • Which type of anemia can be caused by the common treatment for polycythemia vera, which is used to manage patient symptoms?
    • Mastocytosis
      • Mastocytosis
      • Mast Cell Leukemia (MCL)
    • Myeloproliferative Neoplasm, Unclassifiable (MPN-u)
      • Myeloproliferative Neoplasms, Unclassifiable (MPD-u)
  • Summary
      • Table: Laboratory Findings Associated with Myeloproliferative Neoplasms (MPNs)
  • References
      • References

Additional Information

Level of instruction: Intermediate

Intended Audience: Medical laboratory scientists, medical technologists, and technicians. This course is also appropriate for medical laboratory science students and pathology residents.
Author information: Leah Coppolino, MPH, CLS(NCA), MT(ASCP) is the Director of Education and Outreach in the Department of Pathology and Laboratory Medicine at St. Christopher’s Hospital for Children in Philadelphia, Pennsylvania. She holds a Masters in Public Health from Thomas Jefferson University.
Reviewer information: Rebecca J. Laudicina, PhD, MLS(ASCP)CM is Professor Emeritus in the Division of Clinical Laboratory Science at The University of North Carolina at Chapel Hill’s School of Medicine. She obtained a Master of Education and PhD in Educational Psychology from Temple University. She is the author of numerous hematology-related publications.


These are the most common topics and keywords covered in Myeloproliferative Neoplasms:

extramedullary epinephrine myelogenous precursors mutation hemoglobin thromboplastin anemia criterion gene blood phlebotomy aggregation deficiency eosinophilia disorders over-proliferation numbers erythroid exon hepatosplenomegaly diagnosis breathunexplained health chromosomes eosinophilic syndrome ratio karyotypic lymphocytic morphology chromosome fibrosis erythrocytic adenosine thrombopoeitinusually thrombocytosis hypereosinophilic stem red blood cell symptoms aspiration leukocyte platelets wbcs neoplasmmost hematologic abnormality lplatelet bleedingpetechiaenight diphosphate mastocytosis megakaryocyte neutrophils jak2 phosphatase clonality diseases lung wright-stained clinical erythropoietin aspirate neoplasm monocytes myelofibrosis transformation indolent immature cavity prothrombin dysplasia calreticulin clumps fibrotic megakaryocytic bone marrow asymptomatic neutrophilic thrombopoietin abnormal cobalamin hypercellularity treatment serum turnover megakaryocytes reticulin diagnose polycythemia subtype thrombocythemia lactate unclassifiable hematopoiesis splenomegaly interferon low-dose mast cells hematopoietic cure myeloiderythroid thrombotic erythrocyte leukemia mpn-u neoplastic cytogenetic progenitor platelet dehydrogenase lymphoblastic neoplasms abnormalities somatic cellularity biopsy eosinophils granulocytes transformational myeloid linechronic neutrophilia evaluation iron hypercellular reactive prefibrotic fibrous acute eosinophil dysplastic red blood cells malignant tyrosine philadelphia recommends mast cell cancer peripheral blood smear laboratory myelofibrosisfibroblastpolycythemia unsuccessful hematocrit heart disease mpns protocols poikilocytosis alkaline granulocytic cancertopics abl1 basophils chemotherapy conditions losseasy cutaneous tryptase lineage cellular hydroxyurea kinase diagnostic translocation includenormal erythrocytosis cells answers myeloproliferative leukemic lhemoglobin clonal myelodysplastic clones
How to Subscribe
MLS & MLT Comprehensive CE Package
Includes 94 CE courses, most popular
$95 Add to cart
Pick Your Courses
Up to 8 CE hours
$50 Add to cart
Individual course$20 Add to cart

BM biopsy megakayocytes abnormal

Chronic Myelogenous Leukemia. Peripheral Blood Smear.
Image Credit: Paulo Henrique Orlandi Mourao

Bacterial infection, many neutrophils




therapeutic phlebotomy from ITXMdiagnostics website with permission 8-2014 LC