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Myeloproliferative Neoplasms (Online CE Course)

(based on 390 customer ratings)

Author: Leah Coppolino, MPH, CLS(NCA), MT(ASCP)
Reviewer: Rebecca J. Laudicina, PhD, MLS(ASCP)CM

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Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 1 hour(s)
Course number 578-011-17, approved through 2/28/2019
Course number 20-547797, approved through 9/1/2018

Objectives

  • Describe the 2008 World Health Organization classification system for myeloproliferative neoplasms (MPNs).
  • Compare and contrast the types of MPNs based upon etiology and patient symptoms.
  • Discuss the hematologic, cytogenetic, and other laboratory features associated with specific MPNs.
  • List common treatment options.

Customer Ratings

(based on 390 customer ratings)

Course Outline

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Additional Information

Level of instruction: Intermediate

Intended Audience: Medical laboratory scientists, medical technologists, and technicians. This course is also appropriate for medical laboratory science students and pathology residents.
 
Author information: Leah Coppolino, MPH, CLS(NCA), MT(ASCP) is the Director of Education and Outreach in the Department of Pathology and Laboratory Medicine at St. Christopher’s Hospital for Children in Philadelphia, Pennsylvania. She holds a Masters in Public Health from Thomas Jefferson University.
 
Reviewer information: Rebecca J. Laudicina, PhD, MLS(ASCP)CM is Professor Emeritus in the Division of Clinical Laboratory Science at The University of North Carolina at Chapel Hill’s School of Medicine. She obtained a Master of Education and PhD in Educational Psychology from Temple University. She is the author of numerous hematology-related publications.

BM biopsy megakayocytes abnormal
Chronic Myelogenous Leukemia. Peripheral Blood Smear.
Image Credit: Paulo Henrique Orlandi Mourao
Bacterial infection, many neutrophils
CML
CMLspread
pt16-basophil
therapeutic phlebotomy from ITXMdiagnostics website with permission 8-2014 LC

Keywords

These are the most common topics and keywords covered in Myeloproliferative Neoplasms:

erythropoietin diagnosis mast cells leukemia polycythemia cancertopics low-dose erythrocyte eosinophil translocation reticulin conditions hypereosinophilic somatic diseases asymptomatic deficiency turnover abnormalities clonal hypercellularity heart dysplasia hydroxyurea hematocrit myelodysplastic linechronic extramedullary includenormal diphosphate acute criterion clonality neoplastic transformation thrombocytosis immature abnormality gene calreticulin interferon thrombopoeitinusually wright-stained stem eosinophils cells lymphocytic erythrocytosis chemotherapy iron syndrome over-proliferation cytogenetic progenitor hemoglobin cellular wbcs myelogenous leukemic adenosine epinephrine precursors eosinophilic bone marrow neutrophilia clones cure answers cutaneous lineage tyrosine disorders ratio bleedingpetechiaenight breathunexplained platelet malignant jak2 lactate red blood cell abl1 clumps megakaryocytes hepatosplenomegaly myeloproliferative myeloiderythroid lhemoglobin reactive granulocytic symptoms mutation treatment hematologic losseasy hematopoiesis exon cavity peripheral blood smear lplatelet numbers granulocytes neoplasms monocytes biopsy unsuccessful disease prothrombin myelofibrosisfibroblastpolycythemia hypercellular thromboplastin chromosome aspirate phlebotomy aspiration erythrocytic lung karyotypic mastocytosis myeloid megakaryocyte cancer health megakaryocytic kinase philadelphia transformational splenomegaly evaluation platelets prefibrotic indolent laboratory chromosomes fibrotic abnormal basophils thrombotic red blood cells blood eosinophilia mpns dysplastic neoplasmmost phosphatase unclassifiable subtype erythroid neoplasm thrombocythemia fibrous lymphoblastic serum mast cell tryptase diagnose fibrosis hematopoietic alkaline neutrophils recommends protocols morphology cellularity clinical aggregation poikilocytosis mpn-u myelofibrosis thrombopoietin leukocyte cobalamin dehydrogenase anemia diagnostic neutrophilic
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BM biopsy megakayocytes abnormal


Chronic Myelogenous Leukemia. Peripheral Blood Smear.
Image Credit: Paulo Henrique Orlandi Mourao


Bacterial infection, many neutrophils


CML


CMLspread


pt16-basophil


therapeutic phlebotomy from ITXMdiagnostics website with permission 8-2014 LC