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Myeloproliferative Neoplasms (Online CE Course)

(based on 361 customer ratings)

Author: Leah Coppolino, MPH, CLS(NCA), MT(ASCP)
Reviewer: Rebecca J. Laudicina, PhD, MLS(ASCP)CM

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Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 1 hour(s)
Course number 578-011-17, approved through 2/28/2019
Course number 20-547797, approved through 9/1/2020

Objectives

  • Describe the 2008 World Health Organization classification system for myeloproliferative neoplasms (MPNs).
  • Compare and contrast the types of MPNs based upon etiology and patient symptoms.
  • Discuss the hematologic, cytogenetic, and other laboratory features associated with specific MPNs.
  • List common treatment options.

Customer Ratings

(based on 361 customer ratings)

Course Outline

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Additional Information

Level of instruction: Intermediate

Intended Audience: Medical laboratory scientists, medical technologists, and technicians. This course is also appropriate for medical laboratory science students and pathology residents.
 
Author information: Leah Coppolino, MPH, CLS(NCA), MT(ASCP) is the Director of Education and Outreach in the Department of Pathology and Laboratory Medicine at St. Christopher’s Hospital for Children in Philadelphia, Pennsylvania. She holds a Masters in Public Health from Thomas Jefferson University.
 
Reviewer information: Rebecca J. Laudicina, PhD, MLS(ASCP)CM is Professor Emeritus in the Division of Clinical Laboratory Science at The University of North Carolina at Chapel Hill’s School of Medicine. She obtained a Master of Education and PhD in Educational Psychology from Temple University. She is the author of numerous hematology-related publications.

BM biopsy megakayocytes abnormal
Chronic Myelogenous Leukemia. Peripheral Blood Smear.
Image Credit: Paulo Henrique Orlandi Mourao
Bacterial infection, many neutrophils
CML
CMLspread
pt16-basophil
therapeutic phlebotomy from ITXMdiagnostics website with permission 8-2014 LC

Keywords

These are the most common topics and keywords covered in Myeloproliferative Neoplasms:

clinical diagnosis cutaneous basophils platelet blood over-proliferation cells lung dehydrogenase alkaline erythroid progenitor chromosome splenomegaly abl1 neoplasm hematologic chromosomes transformation abnormality disorders abnormalities erythrocyte leukocyte eosinophilic cobalamin cancertopics eosinophils peripheral blood smear iron mpn-u ratio lactate neoplasmmost red blood cells eosinophilia fibrosis tyrosine somatic deficiency hematocrit mpns syndrome diphosphate eosinophil asymptomatic cytogenetic prefibrotic unclassifiable unsuccessful monocytes epinephrine granulocytic neutrophils dysplasia myeloiderythroid erythrocytic bleedingpetechiaenight interferon malignant symptoms adenosine lhemoglobin conditions polycythemia platelets dysplastic thrombocythemia mast cell includenormal tryptase clones myeloproliferative evaluation hypereosinophilic neutrophilic hepatosplenomegaly anemia acute wright-stained answers granulocytes heart immature cellular low-dose karyotypic kinase breathunexplained fibrous prothrombin cancer leukemia clumps hemoglobin cavity reactive megakaryocyte criterion turnover megakaryocytes numbers neoplasms diseases thrombotic hypercellular laboratory precursors treatment myeloid lymphoblastic health clonal erythrocytosis calreticulin phosphatase exon hydroxyurea diagnostic cure myelofibrosisfibroblastpolycythemia extramedullary diagnose jak2 clonality leukemic fibrotic wbcs cellularity chemotherapy biopsy hematopoiesis lymphocytic gene transformational mast cells bone marrow aspirate thrombocytosis mutation disease myelofibrosis myelodysplastic linechronic thrombopoeitinusually morphology philadelphia thrombopoietin hypercellularity subtype translocation reticulin lplatelet aspiration neoplastic poikilocytosis aggregation myelogenous serum thromboplastin red blood cell mastocytosis recommends megakaryocytic hematopoietic phlebotomy protocols stem losseasy neutrophilia indolent erythropoietin lineage abnormal
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BM biopsy megakayocytes abnormal


Chronic Myelogenous Leukemia. Peripheral Blood Smear.
Image Credit: Paulo Henrique Orlandi Mourao


Bacterial infection, many neutrophils


CML


CMLspread


pt16-basophil


therapeutic phlebotomy from ITXMdiagnostics website with permission 8-2014 LC