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Myeloproliferative Neoplasms (Online CE Course)

(based on 384 customer ratings)

Author: Leah Coppolino, MPH, CLS(NCA), MT(ASCP)
Reviewer: Rebecca J. Laudicina, PhD, MLS(ASCP)CM

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Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 1 hour(s)
Course number 578-011-17, approved through 2/28/2019
Course number 20-547797, approved through 9/1/2018

Objectives

  • Describe the 2008 World Health Organization classification system for myeloproliferative neoplasms (MPNs).
  • Compare and contrast the types of MPNs based upon etiology and patient symptoms.
  • Discuss the hematologic, cytogenetic, and other laboratory features associated with specific MPNs.
  • List common treatment options.

Customer Ratings

(based on 384 customer ratings)

Course Outline

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Additional Information

Level of instruction: Intermediate

Intended Audience: Medical laboratory scientists, medical technologists, and technicians. This course is also appropriate for medical laboratory science students and pathology residents.
 
Author information: Leah Coppolino, MPH, CLS(NCA), MT(ASCP) is the Director of Education and Outreach in the Department of Pathology and Laboratory Medicine at St. Christopher’s Hospital for Children in Philadelphia, Pennsylvania. She holds a Masters in Public Health from Thomas Jefferson University.
 
Reviewer information: Rebecca J. Laudicina, PhD, MLS(ASCP)CM is Professor Emeritus in the Division of Clinical Laboratory Science at The University of North Carolina at Chapel Hill’s School of Medicine. She obtained a Master of Education and PhD in Educational Psychology from Temple University. She is the author of numerous hematology-related publications.

BM biopsy megakayocytes abnormal
Chronic Myelogenous Leukemia. Peripheral Blood Smear.
Image Credit: Paulo Henrique Orlandi Mourao
Bacterial infection, many neutrophils
CML
CMLspread
pt16-basophil
therapeutic phlebotomy from ITXMdiagnostics website with permission 8-2014 LC

Keywords

These are the most common topics and keywords covered in Myeloproliferative Neoplasms:

extramedullary kinase low-dose phlebotomy mpn-u mutation hypereosinophilic blood lung cutaneous hematocrit gene breathunexplained myeloid abnormality diphosphate red blood cells cells deficiency protocols chromosome myelogenous calreticulin malignant mast cells disorders unclassifiable neoplasms dehydrogenase recommends hemoglobin laboratory prefibrotic platelets poikilocytosis fibrous ratio clonal adenosine hepatosplenomegaly turnover transformation iron granulocytes clumps interferon abnormalities erythroid epinephrine hypercellular thromboplastin translocation treatment eosinophilia erythrocyte leukocyte neutrophils acute lhemoglobin myeloproliferative cytogenetic bone marrow answers granulocytic evaluation monocytes cancertopics chromosomes megakaryocytic aspiration diseases aspirate symptoms stem lymphoblastic platelet eosinophil diagnostic cellular neoplastic anemia erythropoietin abl1 mastocytosis disease alkaline eosinophilic dysplasia cellularity hematologic thrombocythemia splenomegaly serum chemotherapy leukemic karyotypic basophils neoplasmmost phosphatase losseasy hematopoiesis aggregation myelofibrosis wbcs cavity lplatelet tryptase morphology hypercellularity clones reticulin lactate linechronic transformational conditions red blood cell precursors myeloiderythroid indolent includenormal mpns neoplasm philadelphia numbers diagnosis clonality somatic cure neutrophilic lymphocytic myelodysplastic progenitor reactive subtype mast cell cancer prothrombin criterion abnormal dysplastic hydroxyurea eosinophils megakaryocyte erythrocytosis polycythemia megakaryocytes tyrosine unsuccessful peripheral blood smear bleedingpetechiaenight hematopoietic immature fibrotic thrombotic heart health fibrosis myelofibrosisfibroblastpolycythemia cobalamin diagnose thrombocytosis syndrome clinical biopsy asymptomatic lineage erythrocytic neutrophilia exon wright-stained over-proliferation jak2 leukemia thrombopoietin thrombopoeitinusually
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BM biopsy megakayocytes abnormal


Chronic Myelogenous Leukemia. Peripheral Blood Smear.
Image Credit: Paulo Henrique Orlandi Mourao


Bacterial infection, many neutrophils


CML


CMLspread


pt16-basophil


therapeutic phlebotomy from ITXMdiagnostics website with permission 8-2014 LC