Course Outline
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- Human Papillomavirus (HPV)
- Introduction: HPV and Cervical Cancer
- Organizations and Agencies
- HPV as a Virus
- HPV Structure
- HPV Viral Types
- Low-Risk and High-Risk HPV Types
- HPV Genome and Proteins
- Which of the following HPV types are high-risk HPV types and most commonly isolated in cervical caners?
- Select the statement that correctly describes the HPV genome and its encoded proteins.
- HPV as a Sexually Transmitted Infection (STI)
- HPV as a Sexually Transmitted Infection (STI)
- Clinical Diseases Caused by HPV STI Types
- Most genital condylomas and cervical lesions caused by HPV resolve as a result of the immune response in the infected individual.
- Which HPV virus types do not cause cancer but can account for 90% of all genital warts?
- Cervical Cancer and HPV Types
- Papanicolaou (Pap) Test and Cervical Cytology Testing
- Overview of the Pap Smear
- Cervical Cancer Diagnostic Procedures
- _____________ is a diagnostic procedure that examines an illuminated, magnified view of the cervix, vagina, and vulva, usually when an abnormality is ...
- HPV Molecular Diagnostics
- Molecular Detection of HPV
- Molecular Detection of HPV in Cervical Cytology Specimens
- Review: Nucleic Acids and Molecular Diagnostic Testing
- Molecular Testing Basics
- Hybridization
- Amplification
- Review the descriptions of molecular testing techniques and select the correct statements.
- Types of Molecular HPV Testing
- Updated Guidelines for Cervical Cancer Screening
- Prevention of HPV
- References
Additional Information
Level of instruction: Intermediate
Intended Audience: Medical laboratory scientists and technicians and other health care personnel who have an interest in this subject matter. This course is also appropriate for medical laboratory science students, pathology residents, and practicing pathologists.
Author information: Mary Ellen Koenn, MS, MLS(ASCP) is an associate professor emeritus, West Virginia University School of Medicine, Medical Laboratory Science Program. During her career as a medical technologist and educator, she has been a laboratory supervisor and manager and has held several teaching positions. She is the author of numerous articles for laboratory publications and textbook chapters and is a frequent presenter at laboratory seminars and workshops. Ms. Koenn holds a Master of Science degree in Medical Technology.
Reviewer information: Laurie Bjerklie, M.A., MLS(ASCP)CM is
currently a Content Developer for MediaLab and LabCE. She earned a B.S. in
Medical Laboratory Science from the University of North Dakota
and an M.A. in Curriculum and Instruction from Saint Xavier University. She has
over 14 years of experience in higher education and has held
faculty positions in both MLT and MLS programs. She most recently served as the
Program Manager of Medical Laboratory Science at Saint Louis University.
Course Description: This course discusses the various types of human papillomavirus and their association with cervical cancer. Molecular methods of detection are discussed, beginning with a basic review of nucleic acid amplification methods and hybridization methods. Two FDA-approved methods for molecular HPV testing are briefly explained. The course also presents four case studies to demonstrate the correct and incorrect utilization of HPV molecular methods.