Human Papillomavirus (HPV) and Molecular Testing for Cervical Cancer (Online CE Course)

(based on 380 customer ratings)

Author: Mary Ellen Koenn, MS, MLS(ASCP)
Reviewer: Laurie Bjerklie, MA, MLS(ASCP)CM

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Human papillomavirus (HPV) is a frequently occurring viral infection that is sexually transmitted. HPV infections often present with mild symptoms or are asymptomatic and do not always progress to a disease state. However, some HPV infections can cause cervical or other anogenital carcinomas. If HPV screening is done regularly, most cervical cancers can be prevented. In fact, cervical cancer is one of the most successfully treated cancers. Management of HPV has changed dramatically with the introduction of DNA methods for diagnosis of HPV infections, and vaccines for the prevention of HPV infections. This course is intended to increase your knowledge about HPV and to acquaint you with molecular methods that are currently available for detection of HPV DNA in cervical cells.

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Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 2 hour(s)
Approved through 11/30/2024
Florida Board of Clinical Laboratory Personnel Credit Hours - General (Molecular Pathology): 2 hour(s)
Approved through 11/30/2024

Objectives

  • Describe human papillomavirus (HPV) structure, genome, and encoded proteins.
  • Identify high-risk and low-risk HPV types and the relationship between HPV and cervical cancer.
  • Identify the symptoms, causes, and risk factors associated with cervical cancer.
  • Describe the carcinogenesis of cervical cancer including a description of tumor suppressor genes, oncogenes, and the virulence of HPV types 16 and 18.
  • Compare and contrast the FDA-approved molecular assays for high risk HPV types.
  • Compare and contrast vaccines to prevent HPV infections.
  • Evaluate appropriate and inappropriate utilization of molecular testing for HPV DNA in cervical cancer screening.
  • Discuss basic molecular diagnostic processes: denaturation, hybridization, and types of amplification methods.
  • Describe the FDA-approved cobas HPV test for primary cervical cancer screening.
  • Summarize and contrast the latest cervical cancer screening guidelines issued by the professional organizations and discuss the use of the HPV test as a primary cervical cancer screen.

Customer Ratings

(based on 380 customer ratings)

Course Outline

Click on the links below to preview selected pages from this course.
  • Human Papillomavirus (HPV)
    • HPV as a Virus
      • HPV Structure
      • HPV Viral Types
      • Low-Risk and High-Risk HPV Types
      • HPV Genome and Proteins
      • Which of the following HPV types are high-risk HPV types and most commonly isolated in cervical caners?
      • Select the statement that correctly describes the HPV genome and its encoded proteins.
    • HPV as a Sexually Transmitted Infection (STI)
      • HPV as a Sexually Transmitted Infection (STI)
      • Clinical Diseases Caused by HPV STI Types
      • Most genital condylomas and cervical lesions caused by HPV resolve as a result of the immune response in the infected individual.
      • Which HPV virus types do not cause cancer but can account for 90% of all genital warts?
    • Cervical Cancer and HPV Types
      • Overview of Cervical Cancer
      • Symptoms, Causes, and Risk Factors for Cervical Cancer
      • Staging of Cervical Cancer
      • Cervical Cancer Treatment and Prognosis
      • Cervical IntraepitheIial Neoplasia (CIN) and Immune Mediated Regression
      • Life Cycle of Human Papillomavirus
      • Review: Tumor Suppressor Genes, Proto-Oncogenes, and Oncogenes
      • Carcinogenesis of Cervical Cancer
      • HPV infection can linger for years in cervical cells and eventually convert normal cells into malignant cells.
      • Which gene or genes in HPV control(s) the production of E6 and E7 in the normal viral life cycle?
    • Papanicolaou (Pap) Test and Cervical Cytology Testing
      • Overview of the Pap Smear
      • Cervical Cancer Diagnostic Procedures
      • What is a diagnostic procedure that examines an illuminated, magnified view of the cervix, vagina, and vulva, usually when an abnormality is found and...
  • HPV Molecular Diagnostics
  • Updated Guidelines for Cervical Cancer Screening
      • Updated Cervical Cancer Screening Guidelines for Pap and HPV Testing
  • Prevention of HPV
  • References

Additional Information

Level of instruction: Intermediate

Intended Audience: Medical laboratory scientists and technicians and other health care personnel who have an interest in this subject matter. This course is also appropriate for medical laboratory science students, pathology residents, and practicing pathologists. 
Author information: Mary Ellen Koenn, MS, MLS(ASCP) is an associate professor emeritus, West Virginia University School of Medicine, Medical Laboratory Science Program. During her career as a medical technologist and educator, she has been a laboratory supervisor and manager and has held several teaching positions. She is the author of numerous articles for laboratory publications and textbook chapters and is a frequent presenter at laboratory seminars and workshops. Ms. Koenn holds a Master of Science degree in Medical Technology.
Reviewer information: Laurie Bjerklie, M.A., MLS(ASCP)CM is currently a Content Developer for MediaLab and LabCE. She earned a B.S. in Medical Laboratory Science from the University of North Dakota and an M.A. in Curriculum and Instruction from Saint Xavier University. She has over 14 years of experience in higher education and has held faculty positions in both MLT and MLS programs. She most recently served as the Program Manager of Medical Laboratory Science at Saint Louis University.

Course Description: This course discusses the various types of human papillomavirus and their association with cervical cancer. Molecular methods of detection are discussed, beginning with a basic review of nucleic acid amplification methods and hybridization methods. Two FDA-approved methods for molecular HPV testing are briefly explained. The course also presents four case studies to demonstrate the correct and incorrect utilization of HPV molecular methods.

How to Subscribe
MLS & MLT Comprehensive CE Package
Includes 180 CE courses, most popular
$109Add to cart
Pick Your Courses
Up to 8 CE hours
$55Add to cart
Individual course$25Add to cart
Abnormal Pap


DNA-_RNA_HPV


luminometer


HPV image_small


p6_HPV genome


HPV capsid