HIV: Structure, Replication, and Detection (Online CE Course)

(based on 241 customer ratings)

Author: Garland E. Pendergraph, PhD, JD, MLS(ASCP)SMCM, HCLD(ABB)
Reviewer: Andrea Gordon, M.Ed., MLS(ASCP)SH

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This introductory-level course is designed to meet requirements for HIV/AIDS training, as well as provide basic information about structure and the mechanisms and proteins involved in replication. Appropriate for continuing education for all laboratory personnel. Dr. Pendergraph's extensive experience teaching in the laboratory environment ensures that you get the training you need for your safety and your requirements.

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Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 1 hour(s)
Approved through 10/31/2025
Florida Board of Clinical Laboratory Personnel Credit Hours - General (Serology/Immunology): 1 hour(s)
Approved through 10/31/2025


  • Explain the basic structure of HIV.
  • Discuss the process by which HIV replicates.
  • Discuss commonly used laboratory methods for detection of HIV infection.
  • Compare the advantages and disadvantages of commonly used laboratory test methods for detection of HIV infection.

Customer Ratings

(based on 241 customer ratings)

Course Outline

Click on the links below to preview selected pages from this course.
  • Structure of the Human Immunodeficiency Virus
      • HIV Introduction and Structure
      • The Genome
      • The Capsid
      • The Envelope
      • Viral Proteins
      • Viral proteins are identified as either glycoprotein (gp) or protein (p). What is indicated by the number that follows the "gp" or "p" designation, fo...
      • Which of the following HIV-1 viral proteins are associated with the envelope?
  • HIV Virus Classifications
      • Mutations
      • Most HIV-1 infections are classified as which one of the following groups?
  • HIV Replication Cycle
      • Overview
      • Stages of Infection
      • Binding
      • Fusion
      • Reverse Transcription
      • Integration
      • Assembly
      • Budding
      • HIV Replication Cycle Infographic
      • Which of the following cells are primary targets of the HIV virus?
      • What is the protein that coats the genome in the core of the HIV-1 virion?
      • True or False: The enzyme found in the core of the HIV virion that is utilized to convert viral RNA into DNA is called reverse transcriptase.
  • Progression of HIV Infection
      • Theories on Host Cell Destruction
      • Stages of HIV Infection
      • Which stage of HIV infection is characterized by a decline in the CD4 T lymphocyte count to less than 200 cells/µL?
  • Laboratory Diagnosis of HIV
      • Overview
      • Types of Assays
      • Antigen/Antibody Tests
      • Antibody Tests
      • Rapid Tests
      • Western Blot
      • Nucleic Acid Testing (NAT)
      • Reverse Transcriptase PCR (RT-PCR)
      • HIV Detection Methods: Comparison Table
      • CDC Recommended Algorithm for HIV Testing
      • Interpreting Results
      • Which of the following HIV tests would be the best choice to detect HIV infection in a high-risk seronegative individual?
      • The CDC recommends that initial screening tests be performed on which of the following kinds of assays?
  • References

Additional Information

Level of Instruction: Intermediate
Intended Audience: Medical laboratory scientists and technicians and other health care personnel who have an interest in this subject matter. This course is also appropriate for medical laboratory science students and pathology residents.
Author Information: Garland E. Pendergraph, PhD, JD, MLS(ASCP)SM, HCLD/CC(ABB) received his MSPH from the University of Kentucky in Lexington, his PhD in medical parasitology and mycology from the University of North Carolina in Chapel Hill, and his law degree with a concentration in health care law from Concord Law School, Purdue University. He also did a Fellowship in Tropical Medicine at Louisiana State University School of Medicine. He is the author of a textbook in phlebotomy, a number of scientific articles, plus internet training programs. He is licensed as a laboratory director in the States of Georgia and Florida.
Reviewer Information: Andrea Gordon, M.Ed., MLS(ASCP)SH holds a master's degree in Community Health Education from Plymouth State University and a bachelor's degree in Medical Technology from the University of New Hampshire. She holds certification as a Medical Laboratory Scientist from the American Society of Clinical Pathology along with a Specialist in Hematology. She has over 25 years of experience as a Program Director for various laboratory science programs. She has approximately 5 years of experience as an administrator in higher education as a VP and Director of Education. Additionally, she has over 15 years of experience as a volunteer for NAACLS.

How to Subscribe
MLS & MLT Comprehensive CE Package
Includes 182 CE courses, most popular
$109Add to cart
Pick Your Courses
Up to 8 CE hours
$55Add to cart
Individual course$25Add to cart
Need multiple seats for your university or lab? Get a quote





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