Hemoglobinopathies: Hemoglobin S Disorders (Online CE Course)

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Author: Lillian Mundt, EdD, MLS(ASCP)SH
Reviewers: David J. Moffa, PhD, BCLD and Joshua J. Cannon, MS, MLS(ASCP)CMSHCM

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Sickle cells are some of the most readily identifiable abnormal red blood cells that may be encountered on a manual differential and observation of them will assist in the positive identification of a hemoglobin S disorder. However, they are not present in all hemoglobin S disorders, or may not be present in all stages of a disorder.


This course will update you on the laboratory testing that is currently being used to diagnose and differentiate between the various forms of hemoglobin S disorders. You will also learn about the clinical symptoms that are associated with each one.

The course concludes with several case studies that will provide you with the opportunity to apply what you learned in the course.

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Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 1.5 hour(s)
Approved through 7/31/2024
Approved through 7/31/2024

Objectives

  • Differentiate among structural abnormalities comprising the hemoglobinopathies.
  • Describe sickle cell disorders and the molecular basis for sickle cell hemoglobins.
  • Describe the process of sickle cell formation and its contributors.
  • List the clinical manifestations of the various forms of sickle cell disorders.
  • Describe therapies used in the treatment of sickle cell disorders.
  • Interpret laboratory findings for sickle cell disorders.
  • Differentiate among the various forms of sickle cell disorders.

Customer Ratings

(based on 184 customer ratings)

Course Outline

Click on the links below to preview selected pages from this course.
  • Hemoglobinopathies
  • Sickle Cell Disorders
      • Sickle Cell Disorders
      • To produce hemoglobin S, glutamic acid that is normally present in the sixth position on the beta globin chain is substituted with which of the follow...
      • Sickle Cell Disorder Frequencies: Hb SS and Hb SA
      • Sickle Cell Disorder Frequency: Hb S with Other Hemoglobins
      • Sickle Cell Disorder Frequency: Hb S / Thalassemia
      • Sickle Cell Disorder Frequency: Hb S with Hereditary Persistence of Fetal Hemoglobin
  • The Sickling Process
  • Clinical Manifestations of Sickle Cell Disease
      • Clinical Manifestations of Sickle Cell Disease (SCD)
      • Vaso-occlusive Crisis
      • Vaso-occlusive Crisis, continued
      • Sequestration Crisis
      • Hemolytic Crisis
      • Aplastic Crisis
      • In sickle cell anemia, an increased amount of which of the following surface antigens on reticulocytes may allow platelets to form a bridge between th...
      • Which of the following will not increase during hemolysis?
      • Complications
      • Risk Factors
      • Which of the following options could cause a sickling event?
  • Treatment of Sickle Cell Disease
  • Laboratory Findings in Sickle Cell Disorders
  • Case Studies
    • Sickle Cell Trait
    • Sickle Cell Disease
      • CBC and RBC Morphology
      • Hemoglobin Electrophoresis
    • Hemoglobin SC Disease
    • Hb S/Beta thalassemia
    • Hb S with Hereditary Persistence of Fetal Hemoglobin (HPFH)
      • CBC and RBC Morphology
      • Hemoglobin Electrophoresis
  • References

Additional Information

Level of instruction: Intermediate
Intended Audience: Medical laboratory scientists, medical laboratory technicians, laboratory supervisors, and laboratory managers. This course is also appropriate for MLS and MLT students and pathology residents.
Author Information: Lillian Mundt, EdD, MLS(ASCP)SH is currently employed by AMITA Adventist Hinsdale Hospital in the Molecular Pathology Department. She received her BA degree in Medical Technology from Aurora College, Aurora, Illinois. Her graduate work was completed at Governor's State University, University Park, Illinois, from which she received her Master of Health Science in Allied Health Professions Education; her doctorate in Educational Leadership was earned from the University of Phoenix. Her work experience includes a position as a medical technologist in hematology for over 30 years at Hinsdale Hospital, Department of Pathology. Lillian also taught at Hinsdale Hospital School of Medical Technology and the Rosalind Franklin University of Medicine and Science Department of Clinical Laboratory Sciences.
Reviewer Information:
David J. Moffa, PhD, BCLD has over 30 years of experience in the healthcare industry as an executive manager, clinical laboratory director, and medical laboratory scientist. He is currently a technical consultant for Kentmere Healthcare, Wilmington, DE, and until his retirement, was the Regional Director for LabCorp, Inc. He holds a PhD in medical biochemistry from the School of Medicine, West Virginia University.
Joshua J. Cannon, MS, MLS(ASCP)CMSHCM received his Bachelor of Science and Master of Science in Medical Laboratory Science from Thomas Jefferson University in Philadelphia, PA. He holds Medical Laboratory Scientist and Specialist in Hematology certifications through the ASCP Board of Certification. He was a professor at Thomas Jefferson University for seven years before transitioning into his current role as Education Developer at MediaLab. His areas of expertise and professional passions include clinical hematology and interprofessional education.

How to Subscribe
MLS & MLT Comprehensive CE Package
Includes 180 CE courses, most popular
$109Add to cart
Pick Your Courses
Up to 8 CE hours
$55Add to cart
Individual course$25Add to cart
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