Course Outline
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- Introduction to erythrocyte inclusions
- Characteristics of polychromatophilic red cells (Reticulocytes)
- Reticulocytes
- Normal Erythrocytes
- Polychromatophilic Red Blood Cells (RBCs)
- Stress Reticulocytes
- Which of the following statements characterize a reticulocyte?
- While performing a peripheral blood smear review, you observe the cells indicated by the arrows on this Wright-Giemsa stained slide.How would you clas...
- Characteristics of Basophilic Stippling
- Basophilic Stippling
- Fine Basophilic Stippling
- Coarse Basophilic Stippling
- What is the composition of the granules associated with basophilic stippling?
- In which of the following disorders would you probably observe coarse basophilic stippling on a Wright-stained peripheral blood smear?
- Characteristics of Howell-Jolly Bodies
- Howell-Jolly Bodies
- Examples of Howell-Jolly Bodies
- Howell-Jolly Body in Nucleated Red Cell
- What is the composition of Howell-Jolly bodies?
- If present, how many Howell-Jolly bodies are usually seen within a given erythrocyte?
- In which of the following conditions would you expect to find Howell-Jolly bodies?
- What abnormality is present in this slide?
- Characteristics of Pappenheimer bodies and Siderotic granules
- Pappenheimer Bodies
- Pappenheimer Bodies, continued
- Pappenheimer Bodies, continued
- Basophilic Stippling contrasted with Pappenheimer Bodies
- Howell-Jolly Bodies and Pappenheimer Bodies
- Comparison of Erythrocyte Inclusions
- Siderotic Granules
- Siderocytes and Ringed Sideroblasts in Bone Marrow
- Siderocyte
- Sideroblast
- Match the descriptions below with the erythrocyte inclusions from the drop down box that they describe. The descriptions refer to the appearance of th...
- Which of the following is NOT present in normal bone marrow and would be associated with a disease or disorder?
- The inclusions that are indicated by the arrows on this Wright-Giemsa stained peripheral blood smear are most likely Pappenheimer bodies.
- The cell that is indicated by the arrow in this Prussian-blue stained bone marrow smear is a ringed sideroblast.
- Characteristics of Cabot Rings
- Cabot Rings
- Cabot Rings, continued
- Cabot Rings, continued
- Which of the following statements best describes the appearance of Cabot rings?
- In which of the following conditions might Cabot rings be observed in erythrocytes on a Wright-stained peripheral blood smear?
- Characteristics of Heinz bodies
- References
Additional Information
Level of Instruction: Intermediate
Intended Audience: Medical laboratory personnel including medical laboratory scientists, medical technologists, medical laboratory technicians. Also appropriate for medical laboratory students, and pathology residents.
Author Information: Betty Smith MT (ASCP) and Jaimy Hill MT (ASCP) developed this course. It was updated by Education Materials for Health Professionals, Inc., under the supervision of Marjorie Spahn MT(ASCP). It was reviewed and adapted for online use by Paul Fekete, M.D. fellow C.A.P.
Reviewer Information: Rory Huschka, M. Ed., MT(ASCP), has over 20 years of combined experience as a medical technologist, technical supervisor, professor, and manager. He is a former Program Director of Clinical Laboratory Science and Medical Laboratory Technician Programs. He is currently a Program Director at MediaLab, Inc. Rory holds a BS degree in Medical Technology from North Dakota State University and a Master's degree in Educational Leadership.
Course Description: This course identifies, describes, and illustrates red blood cell inclusions as they are observed on Wright or Wright-Giemsa-stained peripheral smears. Additional staining procedures that make possible or enhance identification of some erythrocyte inclusions are also discussed. Numerous practice and exam questions reinforce visual recognition skills.
Copyright: This revised course was originally part of a series of courses adapted for the web by MediaLab Inc. under license from Educational Materials for Health Professionals Inc. Dayton OH, 45420. Copyright EMHP Inc.