Case Studies in Hematology - Malignant WBC Disorders (Online CE Course)

Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 1 hour(s) Approved through 1/31/2025

Florida Board of Clinical Laboratory Personnel Credit Hours - General (Hematology): 1 hour(s) Approved through 1/31/2025

Objectives

• Correlate laboratory data with patient history, signs, and symptoms.
• Recognize abnormalities in the CBC and other hematology test results as they pertain to the cases presented.
• Upon reviewing the CBC, recognize which of the tests could indicate a possible malignant condition.
• Analyze the laboratory data and other information given in the case.
• Propose possible diagnoses as well as additional laboratory tests which will help to arrive at a definitive diagnosis of the case.
• Explain the pathophysiological concepts of the malignant disorder in each case.

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Course Outline

• The 2016 WHO Revision of Hematologic Malignancies
• Introduction to the 2016 WHO Classification of Myeloid and Lymphoid Neoplasms
• 2016 WHO Classification of Lymphoid Neoplasms
• The 2016 WHO Classification of Myeloid Neoplasms
• How and why were the lymphoid and myeloid neoplasms reclassified in 2016?
• A Three Year Old with Acute Lymphoblastic Leukemia: A Review of Current and New Diagnostic Tests
• 3 Year Old Child Presenting with Bruising, Lethargy, and Fever
• Interpretation of CBC and Additional Testing
• Immunophenotyping in ALL
• Cytogenetic Analysis
• Molecular Testing
• Discussion of Childhood Acute Lymphoblastic Leukemia
• Immunophenotyping is a useful diagnostic technique to determine cell lineage in acute leukemias. Specifically, this technique detects which of the fol...
• Some favorable factors (i.e., good prognosis) in childhood leukemias include which of the following?
• What is the percentage of blasts that trigger a diagnosis of acute leukemia?
• A 72 Year Old Male with Multiple Myeloma
• Patient Symptoms and Initial Testing
• Discussion and Further Testing
• Further Identification of the M Protein
• Testing for Prognostic Indicators
• Pathophysiology of Multiple Myeloma
• Symptoms and Treatment of Multiple Myeloma
• Symptoms of Multiple Myeloma include which of the following?
• Match the result commonly seen in multiple myeloma to the laboratory test. (Note that not all of these are found in every multiple myeloma patient.)
• Fluorescence In Situ Hybridization (FISH) is a laboratory test frequently performed on multiple myeloma patients. This test detects which of the follo...
• Controversial Diagnosis of Essential Thrombocythemia of a 68-Year-Old Patient
• Initial Laboratory Tests and Presenting Symptoms
• Results of Follow-up Tests and More Testing
• More Tests and a Diagnosis
• Pathophysiology of Essential Thrombocythemia (ET)
• Symptoms and Treatment of ET
• Is This Really the Correct Diagnosis?
• Common laboratory findings at initial diagnosis of Essential Thrombocythemia (ET) include:
• The following criteria must be excluded in order to establish a diagnosis of ET:
• Which of the following diseases is difficult to distinguish from ET?
• A 77 Year Old Man with Dysplasia and Blasts: Myelodysplastic Syndrome with Excess Blasts-2 (MDS-EB-2)
• Symptoms and Initial CBC
• Differential
• Discussion of Results and Further Testing
• Definitive Diagnosis
• Pathophysiology of Myelodysplastic Syndromes (MDS)
• Pathophysiology of MDS-EB2
• Clinical Course, Prognosis and Treatment of MDS-EB2
• Check all the lab results that can be seen in Myelodysplastic Syndromes (MDS):
• Which of the following myelodysplastic syndromes (MDS) is most likely to lead to Acute Myeloid Leukemia (AML)?
• Which of the following abnormal white blood cells can be seen in MDS-EB2?
• References
• References

Additional Information