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- The 2016 WHO Revision of Hematologic Malignancies
- A Three Year Old with Acute Lymphoblastic Leukemia: A Review of Current and New Diagnostic Tests
- 3 Year Old Child Presenting with Bruising, Lethargy, and Fever
- Interpretation of CBC and Additional Testing
- Immunophenotyping in ALL
- Cytogenetic Analysis
- Molecular Testing
- Discussion of Childhood Acute Lymphoblastic Leukemia
- Immunophenotyping is a useful diagnostic technique to determine cell lineage in acute leukemias. Specifically, this technique detects which of the fol...
- Some favorable factors (i.e., good prognosis) in childhood leukemias include which of the following?
- What is the percentage of blasts that trigger a diagnosis of acute leukemia?
- A 72 Year Old Male with Multiple Myeloma
- Patient Symptoms and Initial Testing
- Discussion and Further Testing
- Further Identification of the M Protein
- Testing for Prognostic Indicators
- Pathophysiology of Multiple Myeloma
- Symptoms and Treatment of Multiple Myeloma
- Symptoms of Multiple Myeloma include which of the following?
- Match the result commonly seen in multiple myeloma to the laboratory test. (Note that not all of these are found in every multiple myeloma patient.)
- Fluorescence In Situ Hybridization (FISH) is a laboratory test frequently performed on multiple myeloma patients. This test detects which of the follo...
- Controversial Diagnosis of Essential Thrombocythemia of a 68-Year-Old Patient
- Initial Laboratory Tests and Presenting Symptoms
- Results of Follow-up Tests and More Testing
- More Tests and a Diagnosis
- Pathophysiology of Essential Thrombocythemia (ET)
- Symptoms and Treatment of ET
- Is This Really the Correct Diagnosis?
- Common laboratory findings at initial diagnosis of Essential Thrombocythemia (ET) include:
- The following criteria must be excluded in order to establish a diagnosis of ET:
- Which of the following diseases is difficult to distinguish from ET?
- A 77 Year Old Man with Dysplasia and Blasts: Myelodysplastic Syndrome with Excess Blasts-2 (MDS-EB-2)
- Symptoms and Initial CBC
- Discussion of Results and Further Testing
- Definitive Diagnosis
- Pathophysiology of Myelodysplastic Syndromes (MDS)
- Pathophysiology of MDS-EB2
- Clinical Course, Prognosis and Treatment of MDS-EB2
- Check all the lab results that can be seen in Myelodysplastic Syndromes (MDS):
- Which of the following myelodysplastic syndromes (MDS) is most likely to lead to Acute Myeloid Leukemia (AML)?
- Which of the following abnormal white blood cells can be seen in MDS-EB2?
Level of instruction: Intermediate
Intended Audience: Clinical laboratory technologists and technicians and other health care personnel who have an interest in this subject matter. This course is also appropriate for clinical laboratory science students and pathology residents.
Author Information: Margaret Reinhart MS, MLS(ASCP), is an adjunct instructor of Hematology at the Pennsylvania Hospital Medical Laboratory Science program, which is part of the Hospital of the University of Pennsylvania. From 1990 to 2020, she was the director of the Medical Laboratory Science Program at the University of the Sciences.
Reviewer Information: Rory Huschka, M.Ed., MT(ASCP), has over 20 years of experience as a medical technologist, technical supervisor, professor, and manager. He is the former Director of Medical Laboratory Science and Medical Laboratory Technician Programs at Brookline College. He is currently a Program Director at MediaLab, Inc. Rory holds a BS degree in Medical Technology from North Dakota State University and a Masters in Educational Leadership.
Course Description: This course presents case studies pertaining to malignant/neoplastic disorders. Each case is presented, followed by several pertinent questions. Answers for each question are then given, along with a brief discussion to explain these answers. The course taker will then have the opportunity to answer questions based on the concepts learned in the case.