Case Studies in Hematology - Malignant WBC Disorders (Online CE Course)

(based on 1,117 customer ratings)

Author: Margaret Reinhart, MS, M(LSASCP) Reviewer: Rory Huschka, M.Ed., MLS(ASCP)

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This course presents case studies pertaining to malignant/neoplastic disorders. Each case is presented, followed by several pertinent questions. Answers for each question are then given, along with a brief discussion to explain these answers. The course taker will then have the opportunity to answer questions based on the concepts learned in the case.

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Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 1 hour(s)
Approved through 1/31/2025
Approved through 1/31/2025

Objectives

  • Correlate laboratory data with patient history, signs, and symptoms.
  • Recognize abnormalities in the CBC and other hematology test results as they pertain to the cases presented.
  • Upon reviewing the CBC, recognize which of the tests could indicate a possible malignant condition.
  • Analyze the laboratory data and other information given in the case.
  • Propose possible diagnoses as well as additional laboratory tests which will help to arrive at a definitive diagnosis of the case.
  • Explain the pathophysiological concepts of the malignant disorder in each case.

Customer Ratings

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Course Outline

Click on the links below to preview selected pages from this course.
  • The 2016 WHO Revision of Hematologic Malignancies
      • Introduction to the 2016 WHO Classification of Myeloid and Lymphoid Neoplasms
      • 2016 WHO Classification of Lymphoid Neoplasms
      • The 2016 WHO Classification of Myeloid Neoplasms
      • How and why were the lymphoid and myeloid neoplasms reclassified in 2016?
  • A Three Year Old with Acute Lymphoblastic Leukemia: A Review of Current and New Diagnostic Tests
      • 3 Year Old Child Presenting with Bruising, Lethargy, and Fever
      • Interpretation of CBC and Additional Testing
      • Immunophenotyping in ALL
      • Cytogenetic Analysis
      • Molecular Testing
      • Discussion of Childhood Acute Lymphoblastic Leukemia
      • Immunophenotyping is a useful diagnostic technique to determine cell lineage in acute leukemias. Specifically, this technique detects which of the fol...
      • Some favorable factors (i.e., good prognosis) in childhood leukemias include which of the following?
      • What is the percentage of blasts that trigger a diagnosis of acute leukemia?
  • A 72 Year Old Male with Multiple Myeloma
  • Controversial Diagnosis of Essential Thrombocythemia of a 68-Year-Old Patient
      • Initial Laboratory Tests and Presenting Symptoms
      • Results of Follow-up Tests and More Testing
      • More Tests and a Diagnosis
      • Pathophysiology of Essential Thrombocythemia (ET)
      • Symptoms and Treatment of ET
      • Is This Really the Correct Diagnosis?
      • Common laboratory findings at initial diagnosis of Essential Thrombocythemia (ET) include:
      • The following criteria must be excluded in order to establish a diagnosis of ET:
      • Which of the following diseases is difficult to distinguish from ET?
  • A 77 Year Old Man with Dysplasia and Blasts: Myelodysplastic Syndrome with Excess Blasts-2 (MDS-EB-2)
      • Symptoms and Initial CBC
      • Differential
      • Discussion of Results and Further Testing
      • Definitive Diagnosis
      • Pathophysiology of Myelodysplastic Syndromes (MDS)
      • Pathophysiology of MDS-EB2
      • Clinical Course, Prognosis and Treatment of MDS-EB2
      • Check all the lab results that can be seen in Myelodysplastic Syndromes (MDS):
      • Which of the following myelodysplastic syndromes (MDS) is most likely to lead to Acute Myeloid Leukemia (AML)?
      • Which of the following abnormal white blood cells can be seen in MDS-EB2?
  • References

Additional Information

Level of instruction: Intermediate
 
Intended Audience: Clinical laboratory technologists and technicians and other health care personnel who have an interest in this subject matter. This course is also appropriate for clinical laboratory science students and pathology residents.
 
Author Information: Margaret Reinhart MS, MLS(ASCP), is an adjunct instructor of Hematology at the Pennsylvania Hospital Medical Laboratory Science program, which is part of the Hospital of the University of Pennsylvania. From 1990 to 2020, she was the director of the Medical Laboratory Science Program at the University of the Sciences.
 
Reviewer Information: Rory Huschka, M.Ed., MT(ASCP), has over 20 years of experience as a medical technologist, technical supervisor, professor, and manager. He is the former Director of Medical Laboratory Science and Medical Laboratory Technician Programs at Brookline College. He is currently a Program Director at MediaLab, Inc. Rory holds a BS degree in Medical Technology from North Dakota State University and a Masters in Educational Leadership.
 
Course Description: This course presents case studies pertaining to malignant/neoplastic disorders. Each case is presented, followed by several pertinent questions. Answers for each question are then given, along with a brief discussion to explain these answers. The course taker will then have the opportunity to answer questions based on the concepts learned in the case.

How to Subscribe
MLS & MLT Comprehensive CE Package
Includes 181 CE courses, most popular
$109Add to cart
Pick Your Courses
Up to 8 CE hours
$55Add to cart
Individual course$25Add to cart
A smear with numerous lymphoblasts (ALL L1) (10).


ALL, PAS


multiple myelom resize


Plasma Cells


Serum protein electrophoresis normal and multiple myeloma


Hypogranular neutrophil with a pseudo-Pelger-Huet nucleus in MDS


BM biopsy showing megakaryocytic hyperplasia and clustering consistent with essential thrombocythemia. Used with permission from: S G Holtan, J D Hoyer and F K Buadi.


Plasma cells.  Sheets of plasma cells, as seen in this field of view, are abnormal.  Multiple myeloma must be ruled out. EMHCP417070