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Bone Marrow Aspiration: Normal Hematopoiesis and Basic Interpretive Procedures (Online CE Course)

(based on 308 customer ratings)

Author: Marybeth Helfrich, MT(ASCP)
Reviewer: Paul S. Fekete, MD, FCAP

This course provides a thorough review of cellular elements encountered in normal bone marrow. It also provides guidelines for preparation of smears, including an instructional video, and evaluation and reporting of bone marrows.

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Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 2 hour(s)
Course number 578-010-16, approved through 3/31/2018
Course number 20-547599, approved through 9/1/2018

Objectives

  • Describe bone marrow sample collection, smear preparation and routine staining techniques.
  • Recognize and identify myeloid and erythroid precursors found in normal bone marrow aspirates.
  • Compare lymphocytes, hematogones and plasma cells.
  • Compare and contrast monocytes, monocyte precursors and macrophages.
  • Describe benign background cell types found in normal bone marrow.
  • Outline and explain standard procedures for reporting bone marrow differentials.

Customer Ratings

(based on 308 customer ratings)

Course Outline

Click on the links below to preview selected pages from this course.
  • Bone Marrow Aspirates
      • Introduction to Bone Marrow Aspirates and Biopsies
      • Bone Marrow Biopsy
      • Bone Marrow Aspirate and Biopsy Collection
      • Clinical Laboratory's Role: Bone Marrow Aspirates and Biopsies
      • In which of the following situations would a bone marrow aspirate and biopsy possibly be used as an aid for diagnosis?(Select all that apply)
    • Sample Collection
      • Bone Marrow Collection: Patient Bedside
      • Bone Marrow Delivery
      • The role of the laboratory technologist in processing bone marrow aspirates can vary depending on laboratory and clinician protocols. Which of the fol...
    • Smear techniques
      • Bone marrow Smear Preparation
      • Bone marrow Smear Preparation: Selecting Fragments
      • Long Slide Preparation Techniques: Wedge Smear
      • Long Slide Preparation Techniques: T-prep
      • Long Slide Preparation Techniques: Pull Prep
      • Coverslip Smear Preparation Technique
      • Biopsy Touch Preparation Technique
      • Bone Marrow Smear Techniques Video
      • Which of the following smear techniques can be utilized when processing bone marrow aspirate samples? (Choose all that apply)
    • Routine Staining
  • Normal Bone Marrow Morphology
    • Myeloid Maturation Sequence
      • Myeloblast
      • Promyelocyte
      • Myelocyte
      • Myelocytes: Eosinophils and Basophils
      • Metamyelocyte
      • Band Neutrophil
      • Segmented Neutrophil
      • Place the following stages of neutrophilic granulocyte cellular development in the correct order of maturation, beginning with the earliest form:
    • Erythroid Maturation Sequence
    • Monocytes / Macrophages
    • Lymphocytes / Hematogones / Plasmacells
      • Lymphocyte
      • Hematogone
      • Plasma Cell
      • What are the cells that are indicated by the red arrows in the image on the right?
    • Megakaryocytes
    • Other Constituents of Normal Bone Marrow
  • Bone Marrow Evaluation and Reporting
  • References
      • References

Additional Information

Level of Instruction: Intermediate to Advanced

Intended Audience: Clinical laboratory technologists, technicians, and pathologists. This course is also appropriate for clinical laboratory science students and pathology residents.
 
Author Information: Marybeth Helfrich, MT(ASCP) is currently a Laboratory Technologist Specialist for the Hematology/Oncology Laboratory at Childrens Hospital of Philadelphia. She received her BS, MT from Temple University in Philadelphia and has nearly 40 year experience in both adult and pediatric hematology and oncology settings. She is a regular presenter for ASCLS-PA, has been a presenter for ASCP (local and national), and the Texas Teleconference network. She is responsible for hematology morphology instruction and training for medical technologists and fellows. She is also a regular developer of morphology tutorials for in-house continuing education activities.
 
Reviewer Information: Paul S. Fekete, MD, FCAP is the President and CEO of MediaLab, Inc. He received his MD from Ohio State University and completed his clinical pathology residency at Emory University in Atlanta. He has served as an Assistant Professor of Pathology at Emory and as the Director of Laboratories for Gwinnett Medical Center in Lawrenceville, GA. He is currently Assistant Professor of Pathology, at the Augusta University University of Georgia Medical Partnership. Dr. Fekete is a member of Alpha Omega Alpha Honor Medical Society and a Fellow of the College of American Pathologists.
 
Course information: This course provides a thorough review of cellular elements encountered in normal bone marrow. It also provides guidelines for preparation of smears, including an instructional video, and evaluation and reporting of bone marrows.

2jmml13 sml with arrows
band 2 sml
bm baso + poly sml with arrows 2
cellularity normal sml
progranulocyte sml updated 2
tprep sml LC updated
young megka 1 sml with arrow
plasma 2 sml

Keywords

These are the most common topics and keywords covered in Bone Marrow Aspiration: Normal Hematopoiesis and Basic Interpretive Procedures:

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2jmml13 sml with arrows


band 2 sml


bm baso + poly sml with arrows 2


cellularity normal sml


progranulocyte sml updated 2


tprep sml LC updated


young megka 1 sml with arrow


plasma 2 sml