Body Fluid Differential Tutorial (Online CE Course)

(based on 1,662 customer ratings)

Author: MaryBeth Helfrich, MT(ASCP)
Reviewer: Paul Fekete, MD, FCAP

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If you have forgotten the art of differentiating choroid plexus cells from ependymal cells or viral lymphocytes from fluid monocytes, you are in luck! This course provides a thorough morphologic identification of over 40 cell types and disease states to recharge your memory. The course features over 100 crystal clear, perfectly stained body fluid images to illustrate both basic and advanced cellular morphology - perfect for a comprehensive, detailed review which can help refresh any technologist, both in or out of the hematology laboratory. The course is P.A.C.E. approved for 2 full credit hours to help reach your continuing education credit requirements. Enjoy learning and/or reviewing the key identification characteristics of body fluid cells in a user-friendly and fun format. Enroll today!

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Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 2 hour(s)
Approved through 5/31/2022
Approved through 9/1/2022

Objectives

  • Compare and contrast the morphology of cells found in normal cerebrospinal fluid (CSF), normal pleural fluid, normal peritoneal fluid, and normal synovial fluid.
  • Identify the morphology of cells found in bronchoalveolar lavage (BAL).
  • Distinguish abnormal/reactive/infected cell morphology in fluids.
  • Recognize malignant cell morphology in body fluids.
  • Discuss appropriate scenarios for hematology/pathology review.

Customer Ratings

(based on 1,662 customer ratings)

Course Outline

Click on the links below to preview selected pages from this course.
  • Cytocentrifugation Morphology
  • Cell Types Common To Most Types of Body Fluids
    • Neutrophils
      • Neutrophils
      • Neutrophils, continued
      • Eosinophils vs. Neutrophils
      • Nucleated blood cells will always have the same appearance on a cytocentrifuged smear as they do on a peripheral blood smear.
    • Lymphocytes, Atypical Lymphs, Plasma Cells
      • Normal Lymphocytes
      • Lymphocytes
      • Lymphocytes vs. Monocytes
      • Atypical Lymphocytes vs. Monocytes
      • Lymphocytes and Atypical Lymphocytes
      • Atypical Lymphocytes
      • Viral Lymphocytes
      • Lymphocytes and Plasma Cells in Body Fluids
      • The image on the right is a representative field from a cytospin preparation of a CSF from a patient with a viral infection. Identify the cell indicat...
    • Monocytes and Macrophages
      • Monocytes
      • Monocytes vs Lymphocytes
      • Monocytes and Macrophages
      • Macrophages
      • Phagocytosis
      • Hemosiderin
      • Histiocytes
      • Macrophages are the phagocytes that originate from lymphocytes.
  • Cells Found in Cerebrospinal Fluid
    • Cerebrospinal Fluid: Non-Blood Cells
    • Cerebrospinal Fluid: Bone Marrow Contamination
      • Bone Marrow Contamination in CSF
      • What is the identification of this cellular clump found in CSF? Note the presence of many similar-appearing nuclei without distinct lines of demarcati...
  • Cells Found in Pleural and Peritoneal Fluids
  • Cells Found in Synovial Fluids
  • Cells Found in Bronchoalveolar Lavages
    • Bronchial Lining Cells
      • Bronchial Lining Cells
      • Bronchial Lining Cells, continued
      • Match the following cell types to the body fluids in which they may be seen when the fluid is observed on a cytocentrifuged preparation.
  • Infectious Organisms in Body Fluids
  • Malignant Fluids with Leukemia and Lymphoma.
  • Malignant Fluids with Metastatic Tumor
  • References
      • References

Additional Information

Level of Instruction: Intermediate
 
Intended Audience: This course is intended for laboratory professionals who have experience with peripheral blood morphology and basic experience with body fluid differential analysis.  This tutorial will provide a review of normal and abnormal body fluid morphology utilizing Wright-Giemsa stained cytospin preparations from cerebrospinal fluid (CSF), pleural, peritoneal and synovial fluids as well as bronchial alveolar lavage (BAL) samples.
 
Author Information: Marybeth Helfrich, MT(ASCP) is currently a Laboratory Technologist Specialist for the Hematology/Oncology Laboratory at Children's Hospital of Philadelphia. She received her BS, MT from Temple University in Philadelphia and has nearly 40 years of experience in both adult and pediatric hematology and oncology settings. She is a regular presenter for ASCLS-PA, has been a presenter for ASCP (local and national), and the Texas Teleconference network. She is responsible for hematology morphology instruction and training for medical technologists and fellows. She is also a regular developer of morphology tutorials for in-house continuing education activities.

Reviewer Information: Paul Fekete, MD, FCAP is the President and CEO of MediaLab, Inc. He received his MD from Ohio State University and completed his clinical pathology residency at Emory University in Atlanta. He has served as an Assistant Professor of Pathology at Emory, the Director of Laboratories for Gwinnett Medical Center in Lawrenceville, GA., and President of Gwinnett Pathology Associates.  Dr. Fekete is a member of Alpha Omega Alpha Honor Medical Society and a Fellow of the College of American Pathologists.

Keywords

These are the most common topics and keywords covered in Body Fluid Differential Tutorial:

mesothelial cell demarcation ependymal hemorrhage pericardial lavage diagnosis leukemia bacteria acute multinucleate laboratory vacuolated white blood cells cavity wbcs cytospins granules microbiology identification bacterial histiocyte body pleural fluids lymphocyte cilia clusters mesothelial cells infection vacuoles meningitis plasmacytoid arthritis bronchial brain toxoplasmosis histocytes fungal generous infections cytospin preparations bals intracellular albicans peritoneal fused hospitals melanoma irregularity immature differentials cellular red blood cells nuclearcytoplasmic sterile leukemic organisms translocation cerebrospinal fluid monocyte neural infectious cerebrospinal non-granular rbcs cytoplasm nucleoli adenocarcinoma numbers photos pathology nucleus chemotherapy bowel saline blood primitive nerve mononuclear cells choroid reactive burkitt softer abnormal granulation macrophages hyphae histiocytes multinucleated mesothelium candida lymphocytes burkitts serous neuroectodermal vacuolation lymphoblastic differential rhabdomyosarcoma lymphoma mycobacteria spinal effusions basophilic lymphoid nuclei synovial cytospin metastatic lymph diplococci shaggy textures effusion nuclear cytoplasmic cavities malignant chromatin peripheral blood smear morphology neutrophils lavages samples iron respiratory trauma neuroblastoma clumps protocols cells hematology hemosiderin hospital bi-nucleate disease monocytes tumors mesothelial tumor rectangular cytospin technique peripheral blood smears depicts artifact laboratorians lymphoblasts nervous clinical bone marrow membranes myeloid macrophage pneumonia circulating wright cytospin preparation proportions alveolar ventricles
How to Subscribe
MLS & MLT Comprehensive CE Package
Includes 145 CE courses, most popular
$95Add to cart
Pick Your Courses
Up to 8 CE hours
$50Add to cart
Individual course$20Add to cart
Need multiple seats for your university or lab? Get a quote
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