Body Fluid Differential Tutorial (Online CE Course)

(based on 1,893 customer ratings)

Author: MaryBeth Helfrich, MT(ASCP)
Reviewer: Paul Fekete, MD, FCAP

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If you have forgotten the art of differentiating choroid plexus cells from ependymal cells or viral lymphocytes from fluid monocytes, you are in luck! This course provides a thorough morphologic identification of over 40 cell types and disease states to recharge your memory. The course features over 100 crystal clear, perfectly stained body fluid images to illustrate both basic and advanced cellular morphology - perfect for a comprehensive, detailed review which can help refresh any technologist, both in or out of the hematology laboratory. The course is P.A.C.E. approved for 2 full credit hours to help reach your continuing education credit requirements. Enjoy learning and/or reviewing the key identification characteristics of body fluid cells in a user-friendly and fun format. Enroll today!

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Continuing Education Credits

P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 2 hour(s)
Approved through 5/31/2022
Approved through 9/1/2022

Objectives

  • Compare and contrast the morphology of cells found in normal cerebrospinal fluid (CSF), normal pleural fluid, normal peritoneal fluid, and normal synovial fluid.
  • Identify the morphology of cells found in bronchoalveolar lavage (BAL).
  • Distinguish abnormal/reactive/infected cell morphology in fluids.
  • Recognize malignant cell morphology in body fluids.
  • Discuss appropriate scenarios for hematology/pathology review.

Customer Ratings

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Course Outline

Click on the links below to preview selected pages from this course.
  • Cytocentrifugation Morphology
      • Cytocentrifugation of Body Fluid Samples
  • Cell Types Common To Most Types of Body Fluids
    • Neutrophils
      • Neutrophils
      • Neutrophils, continued
      • Eosinophils vs. Neutrophils
      • Nucleated blood cells will always have the same appearance on a cytocentrifuged smear as they do on a peripheral blood smear.
    • Lymphocytes, Atypical Lymphs, Plasma Cells
      • Normal Lymphocytes
      • Lymphocytes
      • Lymphocytes vs. Monocytes
      • Atypical Lymphocytes vs. Monocytes
      • Lymphocytes and Atypical Lymphocytes
      • Atypical Lymphocytes
      • Viral Lymphocytes
      • Lymphocytes and Plasma Cells in Body Fluids
      • The image on the right is a representative field from a cytospin preparation of a CSF from a patient with a viral infection. Identify the cell indicat...
    • Monocytes and Macrophages
  • Cells Found in Cerebrospinal Fluid
    • Cerebrospinal Fluid: Non-Blood Cells
    • Cerebrospinal Fluid: Bone Marrow Contamination
      • Bone Marrow Contamination in CSF
      • What is the identification of this cellular clump found in CSF? Note the presence of many similar-appearing nuclei without distinct lines of demarcati...
  • Cells Found in Pleural and Peritoneal Fluids
    • Mesothelial cells
  • Cells Found in Synovial Fluids
      • Synovial Lining Cells
      • Synovial Lining Cells, continued
  • Cells Found in Bronchoalveolar Lavages
    • Bronchial Lining Cells
      • Bronchial Lining Cells
      • Bronchial Lining Cells, continued
      • Match the following cell types to the body fluids in which they may be seen when the fluid is observed on a cytocentrifuged preparation.
  • Infectious Organisms in Body Fluids
    • Bacteria
      • Intracellular and Extracellular Bacteria
      • Intracellular Bacteria
      • Peritoneal Lavage Trauma
      • Trauma STAT
      • Septic Arthritis
    • Fungus
      • Yeast
      • Candida albicans - Germ Tube Formation
      • Hyphae
    • Toxoplasma
      • Central Nervous System (CNS) Toxoplasmosis
      • Central Nervous System (CNS) Toxoplasmosis, continued
      • The elements indicated by the arrows were observed on a Wright-stained smear of a synovial fluid. What is the likely identification of the elements an...
  • Malignant Fluids with Leukemia and Lymphoma.
  • Malignant Fluids with Metastatic Tumor
  • References

Additional Information

Level of Instruction: Intermediate
 
Intended Audience: This course is intended for laboratory professionals who have experience with peripheral blood morphology and basic experience with body fluid differential analysis.  This tutorial will provide a review of normal and abnormal body fluid morphology utilizing Wright-Giemsa stained cytospin preparations from cerebrospinal fluid (CSF), pleural, peritoneal and synovial fluids as well as bronchial alveolar lavage (BAL) samples.
 
Author Information: Marybeth Helfrich, MT(ASCP) is currently a Laboratory Technologist Specialist for the Hematology/Oncology Laboratory at Children's Hospital of Philadelphia. She received her BS, MT from Temple University in Philadelphia and has nearly 40 years of experience in both adult and pediatric hematology and oncology settings. She is a regular presenter for ASCLS-PA, has been a presenter for ASCP (local and national), and the Texas Teleconference network. She is responsible for hematology morphology instruction and training for medical technologists and fellows. She is also a regular developer of morphology tutorials for in-house continuing education activities.

Reviewer Information: Paul Fekete, MD, FCAP is the President and CEO of MediaLab, Inc. He received his MD from Ohio State University and completed his clinical pathology residency at Emory University in Atlanta. He has served as an Assistant Professor of Pathology at Emory, the Director of Laboratories for Gwinnett Medical Center in Lawrenceville, GA., and President of Gwinnett Pathology Associates.  Dr. Fekete is a member of Alpha Omega Alpha Honor Medical Society and a Fellow of the College of American Pathologists.

Keywords

These are the most common topics and keywords covered in Body Fluid Differential Tutorial:

saline basophilic proportions shaggy irregularity peripheral blood smears reactive vacuolation cytospins cytoplasm membranes synovial nucleoli granules lymph monocytes brain circulating wright hyphae monocyte pleural adenocarcinoma depicts pneumonia macrophages generous fluids nuclei candida samples lymphocyte leukemia histocytes cytospin preparation diagnosis differentials vacuoles blood nucleus burkitt bals rhabdomyosarcoma hospitals rbcs lymphoblasts respiratory cellular mesothelium differential cerebrospinal fluid fungal iron chemotherapy hemosiderin ependymal infectious bi-nucleate burkitts clinical cytospin technique bacterial trauma lymphocytes neuroblastoma mesothelial bowel nuclearcytoplasmic lymphoid hemorrhage demarcation toxoplasmosis abnormal tumor textures nerve numbers mesothelial cells peripheral blood smear disease wbcs lavage effusions ventricles lymphoma choroid microbiology rectangular neutrophils infection leukemic clumps laboratory cavity cytospin spinal cavities tumors cytoplasmic albicans plasmacytoid morphology histiocytes acute metastatic melanoma neural granulation clusters primitive immature meningitis arthritis vacuolated multinucleate bronchial histiocyte intracellular translocation infections softer lymphoblastic non-granular hematology bacteria macrophage pathology mesothelial cell cells cytospin preparations effusion myeloid body fused cerebrospinal diplococci mycobacteria laboratorians cilia malignant peritoneal lavages nuclear red blood cells identification neuroectodermal serous sterile multinucleated organisms alveolar pericardial white blood cells artifact photos nervous bone marrow mononuclear cells hospital chromatin protocols
How to Subscribe
MLS & MLT Comprehensive CE Package
Includes 137 CE courses, most popular
$95Add to cart
Pick Your Courses
Up to 8 CE hours
$50Add to cart
Individual course$20Add to cart
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