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St. Louis encephalitis neuroinvasive disease by state 2004-2013. Image courtesy CDC.

Epidemiology: SLEV

The number of cases is the United States varies year by year with periodic outbreaks. Most cases occur in the eastern and central US, with some in the western states. Cases are most prevalent in the summer and early fall but may occur year round in the South. Cases are rarely seen outside the US.
People who work or play outdoors are most at risk. Older persons are most at risk for death. The case fatality rate ranges from 5 to 15%. The graph below shows cases of St. Louis encephalitis neuroinvasive disease reported between 2004-2013 by ArboNET/CDC.