The cell representations are listed below.
CD19/CD5 dual + = 0%
Interpretation of the above data (refer to the decision tree to assist with interpretation of the case):
- There is a good mix of kappa and lambda; neither one is predominant.
- The B cells do not express CD5 (a B cell that expresses CD5 is abnormal because CD5 is normally a T cell marker)
- CD10 is not present on the B cells.
- Conclusion: B cells are NORMAL
- The pan T cell markers all are within a few percentage points of one another, which translates to the sample having all markers that should be there and no values are skewed toward one marker.
- CD4 plus CD8 equals the total CD3 (55 + 33 = 88), therefore, there is good representation of both T helper and cytotoxic T cells (a neoplastic process could have predominantly one or the other or dual positive CD4 and CD8).
- Conclude: T cells are NORMAL
Final conclusion: this is a normal peripheral blood lymphocyte population and there is no indication of a neoplastic process. The B cells that are present, though a small percentage of the total lymphocytes, have no abnormal markers. Most of the lymphocytes in this sample are T cells, yet they are normal as well. The CD markers that should be there are present and there is a good representation of both helper and cytotoxic cells.