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The page below is a sample from the LabCE course Hemoglobinopathies: Hemoglobin S Disorders. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Sickle Cell Disorder Frequencies: Hb SS and Hb SA

The sickle cell gene is most prevalent in Africa, although it is also common in Mediterranean countries, India, and the Middle East.

Less than 2% of African-Americans are homozygous for HbS and 8 - 10 % are heterozygous.