There are several antifibrinolytic drugs that can be used during surgery that can reduce bleeding. These include:
- Tranexamic acid -synthetic antifibrinolytic (TA)
- epislon amino caproic acid (EACA)
- *Aprotinin -factor XIII - fibrinogen / calcium chloride dihydrate - thrombin
- *Aprotinin was removed from the US market but it still used in other countries.
The cost of these agents are significant and not all facilities will have them available.
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