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The page below is a sample from the LabCE course
Parasitology Case Studies: Protozoa in Blood (by ASCLS)
. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.
Learn more about Parasitology Case Studies: Protozoa in Blood (by ASCLS) (online CE course)
Rapid Diagnostic Test
CDC
Patient's blood is applied to the sample pad on the test card
Reagents are added
After 15 minutes, specific bands in the test card window indicate whether the patient is infected with
P. falciparum
or one of the other 3 species
Detects HRP2 which is specific to
Plasmodium falciparum
Detects a malaria aldolase found in all four species
Therefore, can only identify
P. falciparum
to the species level--p.f. on the cassette
Cannot distinguish between
Plasmodium vivax
,
Plasmodium ovale,
or
Plasmodium malariae
or detect mixed infections--p.v. on the cassette
Lower concentrations of parasites cannot be detected so all negative RDTs should have thick and thin smears performed
Thin smears are also necessary to determine the correct species of malaria and the level of parasitemia
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