The page below is a sample from the LabCE course Human Papillomavirus (HPV) and Molecular Testing for Cervical Cancer. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Molecular Detection of HPV in Cervical Cytology Specimens

HPV molecular testing involves the detection of HPV viral DNA in cervical cells collected during a pelvic examination. Molecular testing is utilized for detecting high risk-HPV (HR- HPV) types. The testing can be performed as:

  • Primary screening for HPV with or without a Pap test
  • Follow-up on abnormal Pap smear cytology
  • Triage of atypical squamous cells of undetermined significance (ASC-US) Pap smear results