Southern Blot: Employs a restriction endonuclease enzyme to extract DNA from the cells. DNA detection is done using agarose gel electrophoresis.
Fluorescent In Situ Hybridization (FISH): Uses RNA Northern Blot or DNA Southern Blot techniques to detect targets of interest in cytology/histology specimens or other nucleic acid variations.
DNA fingerprinting: Restriction Fragment Length Polymorphism (RFLP): Cuts long DNA into shorter fragments before detection to isolate changes or polymorphisms. These can either be detected by Southern Blot or by Polymerase Chain Reaction (PCR).