The page below is a sample from the LabCE course Pharmacology in the Clinical Lab: Therapeutic Drug Monitoring and Pharmacogenomics. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

Learn more about Pharmacology in the Clinical Lab: Therapeutic Drug Monitoring and Pharmacogenomics (online CE course) »
How to Subscribe
MLS & MLT Comprehensive CE Package
Includes 97 CE courses, most popular
$95 Add to cart
Pick Your Courses
Up to 8 CE hours
$50 Add to cart
Individual course$20 Add to cart

Basic Pharmacokinetics

In order to discuss TDM and PGx we need to also introduce the concept of pharmacokinetics.

Pharmacokinetics is the study of drug disposition in the body: It concerns how and when drugs enter the circulation, how long they remain in the blood, and how they are ultimately eliminated from the body.

TDM is the clinical assessment of a drug's pharmacokinetic properties. Physicians and pharmacists often need to establish that a drug is present at a clinically-effective concentration yet does not reach a toxic concentration.

The next few pages will describe some of the factors that determine a drug's disposition in the body. These factors ultimately decide the need for therapeutic drug monitoring.