In particular, we found that there was a decrease in the production of IL-6 in chronic rejection and an increase in CCL17 and CCL22 with chronic rejection of heart transplants. This was verified several times.
Abbreviations:
- CCR, chemokine receptor containing two adjacent cysteine residues
- CXCR, chemokine receptor containing two cysteine residues separated by a single amino acid residue
- IFN, interferon
- IL, interleukin
- IP-10, interferon-inducible protein 10
- I-TAC, IFN-inducible T-cell α chemoattractant
- mAb, monoclonal antibody
- Mig, monokine induced by IFN-γ
- MIP, macrophage inhibitory protein