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The page below is a sample from the LabCE course Transplantation Medicine: Understanding Macrophages to Improve Patient Care (by ASCLS). Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Chemokine production

In particular, we found that there was a decrease in the production of IL-6 in chronic rejection and an increase in CCL17 and CCL22 with chronic rejection of heart transplants. This was verified several times.
Abbreviations:
  • CCR, chemokine receptor containing two adjacent cysteine residues
  • CXCR, chemokine receptor containing two cysteine residues separated by a single amino acid residue
  • IFN, interferon
  • IL, interleukin
  • IP-10, interferon-inducible protein 10
  • I-TAC, IFN-inducible T-cell α chemoattractant
  • mAb, monoclonal antibody
  • Mig, monokine induced by IFN-γ
  • MIP, macrophage inhibitory protein