RhIg is also indicated in these special circumstances:
- Antepartum fetal maternal hemorrhage (FMH), suspected or proven as a result of placenta previa, amniocentesis, chorionic villus sampling, cordocentesis, other obstetrical manipulative procedures (e.g., external version or abdominal trauma such as may occur in a car accident or fall);
- Therapeutic abortion;
- Vaginal bleeding during pregnancy;
- Loss or threatened loss of fetus at any gestational stage;
- Ectopic pregnancy.
For these non-routine indications, depending on the level of medical care the pregnant woman receives or the awareness level of the risks involved, there is increased potential for RhIg to be administered inappropriately or not at all.