Cold Autoantibodies

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The page below is a sample from the LabCE course Warm Antibodies and Autoantibodies in Blood Banking. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Cold Autoantibodies

Cold autoantibodies are antibodies that act against an individual's own antigens at temperatures below 37o C. These antibodies can be associated with different diseases such as Cold Agglutinin Disease and Paroxysmal Cold Hemoglobinuria. To determine clinical significance of the autoantibody, testing can be performed in the Blood Bank.