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The page below is a sample from the LabCE course Fundamentals of Hemostasis. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Primary Hemostasis – The Vascular System & Platelet Involvement

Platelet aggregation is essential to platelet plug formation because the platelets are now able to span the center of the breach, where there was obviously no exposed collagen to bind to before, as well as clumping behind one another to buttress or strengthen the barrier.

The formation of the platelet plug signals the end of primary hemostasis, and serves to initiate upcoming processes associated with secondary hemostasis.