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The page below is a sample from the LabCE course Pharmacology in the Clinical Lab: Therapeutic Drug Monitoring and Pharmacogenomics. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Pharmacogenomics Definition

Pharmacogenomics (usually abbreviated PGx) is the study of how variations in the human genome affect a given individual's response to medications. It refers to how administered drugs will affect specific patients, given their genetic makeup. Since there are many different genetic mutations and polymorphisms that can affect genes transcribing drug-metabolizing enzymes, different people often respond to the same drug differently.