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The page below is a sample from the LabCE course Variations in White Cell Morphology -- Granulocytes. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Conditions Associated with Hyposegmented Neutrophils

The presence of hyposegmented neutrophils can be an acquired phenomenon, as a result of severe infection, burns, malignancy, chemotherapy or other drugs such as sulfonamides. When the causative agent is removed, the cells will return to normal.
Percentages of neutrophils affected will vary in this condition. Hyposegmented neutrophils as an aquired phenomenon are sometimes referred to as pseudo-Pelger-Huet cells.