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The page below is a sample from the LabCE course Histology Special Stains: Carbohydrates. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Diagnostic Value of Demonstrating Mucopolysaccharides

Dectectable mucin is often present in many disease states. Increased mucin production is indicative of certain adenocarcinomas, including cancers of the pancreas, lung, breast, ovary and colon. Demonstrating mucin can also help differentiate between adenocarcinomas and squamous-cell carcinomas.
 Mucins can be overexpressed in lung diseases such as asthma, bronchitis, chronic obstructive pulmonary disease (COPD), or cystic fibrosis. Staining acid mucins is also useful in diagnosing diseases associated with the gastrointestinal (GI) tract, such as Barrett's esophagus.